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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v1i1.2011</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v1i1.2011</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Association of Hyponatremia with in-Hospital Mortality Among Patients Hospitalized With Stroke</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Kashif</surname>
            <given-names>Hafiz Muhammad</given-names>
          </name>
          <email>hafizkashif254@gmail.com</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Suleman</surname>
            <given-names>Tariq</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Afzal</surname>
            <given-names>Muhammad Naeem</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Raza</surname>
            <given-names>Tabish</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>Department of Medicine &amp; Gastroenterology Services Institute of Medical Science, Services Hospital Lahore</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Hafiz Muhammad Kashif (hafizkashif254@gmail.com)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2020-12-16">
        <day>16</day>
        <month>12</month>
        <year>2020</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2020</year>
      </pub-date>
      <volume>1</volume>
      <issue>1</issue>
      <fpage>45</fpage>
      <lpage>49</lpage>
      <history>
        <date date-type="received" iso-8601-date="2020-09-27">
          <day>27</day>
          <month>09</month>
          <year>2020</year>
        </date>
        <date date-type="accepted" iso-8601-date="2020-10-05">
          <day>05</day>
          <month>10</month>
          <year>2020</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2020 The Author(s)</copyright-statement>
        <copyright-year>2020</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v1i1.2011" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v1i1.2011.pdf" content-type="application/pdf"/>
      <abstract>
        <sec>
          <title>Objective</title>
          <p>The present study helped in clarifying the role of hyponatremia at the time of admission on mortality in stroke patients in Pakistan.</p>
        </sec>
        <sec>
          <title>Methodology</title>
          <p>It was a cohort study, conducted at Medical Unit III, Services Hospital, Lahore, from07-06-2016 to 06-12-2016.One hundred and fifty (75 in each group) patients who fulfilled inclusion criteria were enrolled after written informed consent. Sodium levels was measured on admission and patients were divided in two groups i.e., hyponatremic group comprising of Na</p>
        </sec>
        <sec>
          <title>Results</title>
          <p>The mean age of patients was 63.50 +5.78 with a median of 40 and a mode 42. Most of the patients (53.3%) were above 60 years old and females (54.6%).Among 75 patients who had hyponatremia, 41 patients died in hospital while 34 were discharged from hospital. Among control group, 20 patients died while 55 were discharged from hospital (RR=2.05, P=0.001). This showed that there is strong association between hyponatremia and in-hospital mortality.</p>
        </sec>
        <sec>
          <title>Conclusion</title>
          <p>Hyponatremia is strongly associated with in-hospital patients’ mortality in patients of stroke.</p>
        </sec>
      </abstract>
      <kwd-group xml:lang="en" kwd-group-type="author-keywords">
        <title>Keywords</title>
        <kwd>Hyponatremia</kwd>
        <kwd>In-patient Mortality</kwd>
        <kwd>Stroke.</kwd>
      </kwd-group>
    </article-meta>
  </front>
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  <back>
    <ref-list>
      <title>References</title>
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</article>
