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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v2i4.2179</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v2i4.2179</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Medical Guidelines</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Recommendations for Diagnosis, Treatment &amp; Monitoring of Chronic HCV Infection in Adults</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Hamid</surname>
            <given-names>Saeed</given-names>
          </name>
          <email>saeed.hamid@aku.edu</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Hasnain</surname>
            <given-names>Aliya</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>Department of Medicine, Agha Khan University Karachi, Pakistan</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Saeed Hamid (saeed.hamid@aku.edu)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2021-12-14">
        <day>14</day>
        <month>12</month>
        <year>2021</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2021</year>
      </pub-date>
      <volume>2</volume>
      <issue>4</issue>
      <fpage>349</fpage>
      <lpage>355</lpage>
      <history>
        <date date-type="received" iso-8601-date="2021-08-18">
          <day>18</day>
          <month>08</month>
          <year>2021</year>
        </date>
        <date date-type="accepted" iso-8601-date="2021-10-18">
          <day>18</day>
          <month>10</month>
          <year>2021</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2021 The Author(s)</copyright-statement>
        <copyright-year>2021</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v2i4.2179" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v2i4.2179.pdf" content-type="application/pdf"/>
      <abstract>
        <p>Objectives</p>
        <p>Aim of present recommendations is to optimize Hepatitis C related patient care informed by best available evidence and broad consensus to improve clinical and public health outcomes. The aim is to provide recommendations that are relevant for the confined regional epidemiology of hepatitis C infection as well as healthcare delivery mechanism in Pakistan.</p>
        <p>These recommendations are adapted from World Health Organization (WHO) guide for hepatitis C virus infection targeted particularly for low and middle income countries (LMICs), presenting high burden of disease while treatment is readily available and costs of direct-acting antivirals (DAAs) are on the decline.</p>
      </abstract>
    </article-meta>
  </front>
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  <back>
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