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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v3i3.2243</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v3i3.2243</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Frequency of Asymptomatic Spontaneous Bacterial Peritonitis in Decompensated Cirrhotic Patients with Ascites</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Azhar</surname>
            <given-names>Shahroz</given-names>
          </name>
          <email>shahrozazhar538@gmail.com</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Safdar</surname>
            <given-names>Sidra</given-names>
          </name>
          <xref ref-type="aff" rid="aff2"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Atiq</surname>
            <given-names>Zainab</given-names>
          </name>
          <xref ref-type="aff" rid="aff3"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ishfaq</surname>
            <given-names>Faisal</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Mumtaz</surname>
            <given-names>Sami Ullah</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Abaidullah</surname>
            <given-names>Sajid</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>King Edward Medical University, Mayo Hospital, Lahore</institution>
      </aff>
      <aff id="aff2">
        <institution>Institute of Nuclear Medicine and Oncology (INMOL), Lahore</institution>
      </aff>
      <aff id="aff3">
        <institution>Pakistan Kidney and Liver Institute &amp;Research Center, Lahore</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Shahroz Azhar (shahrozazhar538@gmail.com)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2022-09-12">
        <day>12</day>
        <month>09</month>
        <year>2022</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2022</year>
      </pub-date>
      <volume>3</volume>
      <issue>3</issue>
      <fpage>220</fpage>
      <lpage>224</lpage>
      <history>
        <date date-type="received" iso-8601-date="2022-03-31">
          <day>31</day>
          <month>03</month>
          <year>2022</year>
        </date>
        <date date-type="accepted" iso-8601-date="2022-07-16">
          <day>16</day>
          <month>07</month>
          <year>2022</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2022 The Author(s)</copyright-statement>
        <copyright-year>2022</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v3i3.2243" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/download/file?id=167" content-type="application/pdf"/>
      <abstract>
        <sec>
          <title>Objective</title>
          <p>To determine the frequency of asymptomatic spontaneous bacterial peritonitis in decompensated cirrhotic patients with ascites.</p>
        </sec>
        <sec>
          <title>Methodology</title>
          <p>This was a Cross sectional study conducted at North Medical Ward, Mayo Hospital, Lahore for Six months i.e. August 2019 to January 2020. Total 156 patients fulfilling the selection criteria were enrolled in study from OPD. Patients were advised to present in next morning with overnight fast. Then ascitic fluid sample of 10ml was taken via paracentesis. All samples were sent to the laboratory of the hospital for assessment of spontaneous bacterial peritonitis. Reports were assessed and if absolute neutrophilic count &gt;250/mm3, SAAG &gt;1.1 and positive fluid culture, then spontaneous bacterial peritonitis was labeled.</p>
        </sec>
        <sec>
          <title>Results</title>
          <p>Mean age of patients was 54.121±10.27 years. Among patients 116(74.4%) were male and 40(25.6%) were female. Mean duration of cirrhosis and ascites was 56.13±36.90 and 10.72±12.10 months. Asymptomatic spontaneous bacterial peritonitis was diagnosed in 64(41%) patients. Age of patients (p-value=0.051), Child Pugh class (p-value=0.001) and duration of ascites (p-value=0.000) showed significant association for frequency of Asymptomatic spontaneous bacterial peritonitis.</p>
        </sec>
        <sec>
          <title>Conclusion</title>
          <p>There is higher frequency of asymptomatic spontaneous bacterial peritonitis in decompensated cirrhotic patients with ascites.So all cirrhotic patients with ascites even asymptomatic must undergo abdominal paracentesis for ascitic fluid analysis and/or cultures diagnostic for SBP.</p>
        </sec>
      </abstract>
      <kwd-group xml:lang="en" kwd-group-type="author-keywords">
        <title>Keywords</title>
        <kwd>Asymptomatic</kwd>
        <kwd>Spontaneous</kwd>
        <kwd>Bacterial</kwd>
        <kwd>Peritonitis</kwd>
        <kwd>Decompensated</kwd>
        <kwd>Cirrhotic</kwd>
        <kwd>Ascites.</kwd>
      </kwd-group>
    </article-meta>
  </front>
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  <back>
    <ref-list>
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</article>
