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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v3i4.2261</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v3i4.2261</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Comparison of Effects of Chronic illnesses and Obesity on Health Related Quality of Life</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Rao</surname>
            <given-names>Iqra</given-names>
          </name>
          <email>iqrarao17801@import.invalid</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Fatima</surname>
            <given-names>Iman</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Iqbal</surname>
            <given-names>Javeria</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Siddiq</surname>
            <given-names>Iraj</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Malook</surname>
            <given-names>Qais ul</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Saleemi</surname>
            <given-names>Hurriat</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Yusuf</surname>
            <given-names>Humna</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Sajid</surname>
            <given-names>Hassan</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ahmad</surname>
            <given-names>Hasnaat</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ilyas</surname>
            <given-names>Hasan</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Mukhtar</surname>
            <given-names>Hesham</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>Mayo Hospital Lahore</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Iqra Rao (iqrarao17801@import.invalid)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2022-12-18">
        <day>18</day>
        <month>12</month>
        <year>2022</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2022</year>
      </pub-date>
      <volume>3</volume>
      <issue>4</issue>
      <fpage>306</fpage>
      <lpage>312</lpage>
      <history>
        <date date-type="received" iso-8601-date="2022-08-14">
          <day>14</day>
          <month>08</month>
          <year>2022</year>
        </date>
        <date date-type="accepted" iso-8601-date="2022-10-03">
          <day>03</day>
          <month>10</month>
          <year>2022</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2022 The Author(s)</copyright-statement>
        <copyright-year>2022</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v3i4.2261" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v3i4.2261.pdf" content-type="application/pdf"/>
      <abstract>
        <sec>
          <title>Objective</title>
          <p>The purpose of this study is to compare the degree of impairment among obese and chronically ill children against healthy children in the setting of Mayo Hospital and two public sector schools in Lahore.</p>
        </sec>
        <sec>
          <title>Methodology</title>
          <p>This cross-sectional study included 152 children comprising the age group of 8-12 years recruited via purposive sampling. HRQoL was assessed using PedsQL version 4.0, and a trained interviewer obtained the child's self-report. The ANOVA test was applied to compare subscales and total scores, while significant differences were determined by Bonferroni post hoc test.</p>
        </sec>
        <sec>
          <title>Results</title>
          <p>Mean self-reported total health scores were 84.2 ± 10.4 and 80.0 ± 9.4 in healthy boys and girls, 73.7 ± 23 and 65.5 ± 21.4 in chronically ill boys and girls, 68.3 ± 17 and 63.1 ± 16.3 in obese boys and girls, respectively. The current study's findings indicated least HRQoL scores among obese children as compared to their counterparts. Regarding the subscales, the lowest scores were reported in chronically ill children specifically in physical and school functioning, while obese children reported the lowest scores in emotional and social functioning.</p>
        </sec>
        <sec>
          <title>Conclusion</title>
          <p>Chronic illnesses mainly affect physical and school functioning, while obesity affects emotional and social functioning in children the most. It suggests that awareness be provided regarding childhood obesity to both children and parents and steps be taken to the prevention of childhood obesity and thus improving the standard of living. Moreover, disease processes in early childhood must be diagnosed with early intervention/investigation.</p>
        </sec>
      </abstract>
      <kwd-group xml:lang="en" kwd-group-type="author-keywords">
        <title>Keywords</title>
        <kwd>Obesity</kwd>
        <kwd>Chronic illness</kwd>
        <kwd>Quality of Life</kwd>
        <kwd>Health</kwd>
      </kwd-group>
    </article-meta>
  </front>
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  <back>
    <ref-list>
      <title>References</title>
      <ref id="ref1">
        <label>1</label>
        <mixed-citation>Williams J, Wake M, Hesketh K, Maher E, Waters E. Health-related quality of life of overweight and obese children. JAMA. 2005;293(1):70-6.</mixed-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <mixed-citation>Cantrell MA, Kelly MM. Health-related quality of life for chronically ill children. MCN: Am J Mater/Child Nur. 2015;40(1):24-31.</mixed-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <mixed-citation>Ingerski LM, Modi AC, Hood KK, Pai AL, Zeller M, Piazza-Waggoner C, Driscoll KA, Rothenberg ME, Franciosi J, Hommel KA. Health-related quality of life across pediatric chronic conditions. J Pediat. 2010;156(4):639-44.</mixed-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <mixed-citation>Arabiat DH, Al Jabery MA. Health-related quality of life in pediatric chronic health conditions: A comparative study among children and adolescents in Jordan. Health. 2013;5(11):19.</mixed-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <mixed-citation>Fakhry H, Goldenberg M, Sayer G, Bagot K, Pi S, Ghazzaoui R, et al. Health-related quality of life in childhood cancer. J Develop Behav Pediat. 2013;34(6):419-40.</mixed-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <mixed-citation>Miadich SA, Everhart RS, Borschuk AP, Winter MA, Fiese BH. Quality of life in children with asthma: a developmental perspective. J Pediat Psychol. 2015;40(7):672-9.</mixed-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <mixed-citation>Varni JW, Bendo CB, Nurko S, Shulman RJ, Self MM, Franciosi JP, et al. Health-related quality of life in pediatric patients with functional and organic gastrointestinal diseases. J Pediat. 2015;166(1):85-90.</mixed-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <mixed-citation>Bethell CD, Kogan MD, Strickland BB, Schor EL, Robertson J, Newacheck PW. Key insurance disparities and across-state variations include a national and state profile of leading health problems and health care quality for US children. Acad Pediat. 2011;11(3): S22-33.</mixed-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <mixed-citation>Van Der Lee JH, Mokkink LB, Grootenhuis MA, Heymans HS, Offringa M. Definitions and measurement of chronic health conditions in childhood: a systematic review. JAMA. 2007;297(24):2741-51.</mixed-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <mixed-citation>Haug E, Rasmussen M, Samdal O, Iannotti R, Kelly C, Borraccino A, et al. Overweight in school-aged children and its relationship with demographic and lifestyle factors: results from the WHO-Collaborative Health Behaviour in School-aged Children (HBSC) study. Int J Public Health. 2009;54(2):167-79.</mixed-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <mixed-citation>Hoque ME, Doi SA, Mannan M, Long K, Niessen LW, Mamun AA. Prevalence of overweight and obesity among children and adolescents of the Indian subcontinent: a meta-analysis. Nutr Rev. 2014;72(8):541-50.</mixed-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <mixed-citation>Reilly JJ, Armstrong J, Dorothy AR, Emmett PM, Ness A, Rogers I, Steer C, Sherriff A. Early life risk factors for obesity in childhood: cohort study. BMJ. 2005;330(7504):1357.</mixed-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <mixed-citation>Kaur H, Choi WS, Mayo MS, Harris KJ. Duration of television watching is associated with increased body mass index. J Pediatr. 2003;143: 506-11.</mixed-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <mixed-citation>Wilson N, Quigley R, Mansoor O. Food ads on TV: a health hazard for children. Aus New Zeal J Public Health. 1999;23(6):647-50.</mixed-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <mixed-citation>Nathan BM, Moran A. Metabolic complications of obesity in childhood and adolescence: more than just diabetes. Curr Opin Endocrinol Diab Obes. 2008;15(1):21-9.</mixed-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <mixed-citation>Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Arch Pediat Adol Med. 2003;157(8):821-7.</mixed-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <mixed-citation>Khairy SA, Eid SR, El Hadidy LM, Gebril OH, Megawer AS. The health-related quality of life in normal and obese children. Egypt Pediat Assoc Gazette. 2016;64(2):53-60.</mixed-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <mixed-citation>Wille N, Bullinger M, Holl R, Hoffmeister U, Mann R, Goldapp C, et al. Health-related quality of life in overweight and obese youths: results of a multicenter study. Health Qual Life Outcom. 2010;8(1):36.</mixed-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <mixed-citation>Khodaverdi F, Alhani F, Kazemnejad A, Khodaverdi Z. The relationship between obesity and quality of life in school children. Iranian J Public Health. 2011;40(2):96.</mixed-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <mixed-citation>Jalali-Farahani S, Shojaei FA, Parvin P, Amiri P. Comparison of health-related quality of life (HRQoL) among healthy, obese, and chronically ill Iranian children. BMC Public Health. 2018;18(1):1337.</mixed-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <mixed-citation>Warraich HJ, Javed F, Faraz-ul-Haq M, Khawaja FB, Saleem S. Prevalence of obesity in school-going children of Karachi. PloS one. 2009;4(3):e4816.</mixed-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <mixed-citation>Anwar A, Anwar F, Joiya HU, Ijaz A, Rashid H, Javaid A, Mehmood M. Prevalence of obesity among the school-going children of Lahore and associated factors. J Ayub Med Coll Abbot. 2010;22(4):27-32.</mixed-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <mixed-citation>Pinhas-Hamiel O, Singer S, Pilpel N, Fradkin A, Modan D, Reichman B. Health-related quality of life among children and adolescents: associations with obesity. Int J Obes. 2006;30(2):267.</mixed-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <mixed-citation>Elserougy S, Salama S, Salama I, Shaaban F, Sami S. Effects of obesity and sociodemographic determinants on health-related quality of life in school-aged children in Greater Cairo. Med Res J. 2012;11(1):12-9.</mixed-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <mixed-citation>Marker AM, Steele RG, Noser AE. Physical activity and health-related quality of life in children and adolescents: A systematic review and meta-analysis. Health Psychol. 2018;37(10):893.</mixed-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <mixed-citation>Forhan M, Gill SV. Obesity, functional mobility, and quality of life. Best Pract Res Clin Endocrinol Metabol. 2013;27(2):129-37.</mixed-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <mixed-citation>Riazi A, Shakoor S, Dundas I, Eiser C, McKenzie SA. Health-related quality of life in a clinical sample of obese children and adolescents. Health Qual Life Outcom. 2010;8(1):134.</mixed-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <mixed-citation>Surís JC, Parera N, Puig C. Chronic illness and emotional distress in adolescence. J Adoles Health. 1996;19(2):153-6.</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
