<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD v1.3 20210610//EN" "JATS-archivearticle1-3.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.3" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v3i4.2265</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v3i4.2265</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>To Compare the Frequency of Adverse Outcomes of Severe Versus Mild Oligohydramnios at Full Term</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Zafar</surname>
            <given-names>Abeerah</given-names>
          </name>
          <email>bluestrawberry_2@live.com</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Shauket</surname>
            <given-names>Kamran</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Fatima</surname>
            <given-names>Nida</given-names>
          </name>
          <xref ref-type="aff" rid="aff2"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Abbas</surname>
            <given-names>Sibghat</given-names>
          </name>
          <xref ref-type="aff" rid="aff3"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Nawaz</surname>
            <given-names>Mehwish</given-names>
          </name>
          <xref ref-type="aff" rid="aff4"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Shahbaz</surname>
            <given-names>Samia</given-names>
          </name>
          <xref ref-type="aff" rid="aff5"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>Sahiwal Teaching Hospital Sahiwal</institution>
      </aff>
      <aff id="aff2">
        <institution>BHU Kalri Chiniot</institution>
      </aff>
      <aff id="aff3">
        <institution>THQ Hospital Bhowana Chiniot</institution>
      </aff>
      <aff id="aff4">
        <institution>Mayo Hospital Lahore</institution>
      </aff>
      <aff id="aff5">
        <institution>Shalamar Medical &amp; Dental College, Lahore</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Abeerah Zafar (bluestrawberry_2@live.com)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2022-12-18">
        <day>18</day>
        <month>12</month>
        <year>2022</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2022</year>
      </pub-date>
      <volume>3</volume>
      <issue>4</issue>
      <fpage>331</fpage>
      <lpage>335</lpage>
      <history>
        <date date-type="received" iso-8601-date="2022-07-26">
          <day>26</day>
          <month>07</month>
          <year>2022</year>
        </date>
        <date date-type="accepted" iso-8601-date="2022-09-28">
          <day>28</day>
          <month>09</month>
          <year>2022</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2022 The Author(s)</copyright-statement>
        <copyright-year>2022</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v3i4.2265" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v3i4.2265.pdf" content-type="application/pdf"/>
      <abstract>
        <sec>
          <title>Objective</title>
          <p>Oligohydramnios is a disorder that occurs in pregnancy and is characterized by an amniotic fluid deficiency. To determine the frequency of severe oligohydramnios in pregnant females at term presenting diagnosis of oligohydramnios and to compare the frequency of adverse outcomes of severe versus mild oligohydramnios at term.</p>
        </sec>
        <sec>
          <title>Methodology</title>
          <p>The Descriptive case series was held in Department of Obstetrics and Gynecology, CMH, Okara for 06 months i.e. from 28-12-2019 to 29-6-2020. Keeping in view the inclusion criteria, 100 pregnant females were enrolled. Then females underwent ultrasound and level of AFI was noted. If AFI</p>
        </sec>
        <sec>
          <title>Results</title>
          <p>The mean age group of females was 27.39±3.4 years. The severe oligohydramnios was found in 50 (50%) patients. When were compare the adverse outcome with oligohydramnios we found that the C-section [mild oligohydramnios =26 (52%) &amp; in severe oligohydramnios =33(66%) females], perinatal death [mild oligohydramnios =3(6%) &amp; in severe oligohydramnios =6(12%) females], low Apgar score in [mild oligohydramnios =26(52%) &amp; in severe oligohydramnios=33(66%) females], similarly the low birth weight [mild oligohydramnios =1(2%) &amp; in severe oligohydramnios=2(4%) females]. The adverse outcome showed statistically insignificant difference i.e. p-value&gt;0.05.</p>
        </sec>
        <sec>
          <title>Conclusion</title>
          <p>About half oligohydramnios patients had severe oligohydramnios, while there is no significant association of mild or severe oligohydramnios with adverse feto-maternal outcome.</p>
        </sec>
      </abstract>
      <kwd-group xml:lang="en" kwd-group-type="author-keywords">
        <title>Keywords</title>
        <kwd>Oligohydramnios</kwd>
        <kwd>Adverse Outcome</kwd>
        <kwd>Mild</kwd>
        <kwd>Severe</kwd>
        <kwd>amniotic fluid index</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <!-- <body> omitted: no manuscript (.docx) on file -->
  <back>
    <ref-list>
      <title>References</title>
      <ref id="ref1">
        <label>1</label>
        <mixed-citation>Cunningham F, Leveno K, Bloom S, Spong CY, Dashe J. Amniotic fluid. Williams Obstetrics. 24th ed. New York: Mcgraw-hill; 2014: p. 460-76.</mixed-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <mixed-citation>Souza ASR, Andrade LRd, Silva FLTd, Cavalcanti AN, Guerra GVdQL. Maternal and perinatal outcomes in women with decreased amniotic fluid. Revi Brasi Ginecol Obstet. 2013;35(8):342-8.</mixed-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <mixed-citation>Choi SR. Borderline amniotic fluid index and perinatal outcomes in the uncomplicated term pregnancy. J Mater-Fetal Neonat Med. 2016;29(3):457-60.</mixed-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <mixed-citation>Rathod S, Samal SK. Evaluation of Maternal and Perinatal Outcomes of Induction in Borderline Oligohydramnios at Term. J Clin Diag Res. 2017;11(9):QC05.</mixed-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <mixed-citation>Hashimoto K, Kasdaglis T, Jain S, Atkins K, Harman CR, Baschat AA. Isolated low-normal amniotic fluid volume in the early third trimester: association with adverse perinatal outcomesa. J Peri Med. 2013;41(4):349-53.</mixed-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <mixed-citation>Subash K, Poudel R, Khadka S, Shrestha A. Prevalence of Congenital Anomalies in Oligohydramnios: A Hospital Based Study in Western Nepal. Nepal J Radiol. 2019;9(1):7-11.</mixed-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <mixed-citation>abclawcenters. Oligohydramnios (Low Amniotic Fluid). [updated 2020,cited 2022]; Available from: [https://www.abclawcenters.com/practice-areas/prenatal-birth-injuries/maternal-medical-conditions/oligohydramnios/]</mixed-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <mixed-citation>Chauhan SP, Hendrix NW, Morrison JC, Magann EF, Devoe LD. Intrapartum oligohydramnios does not predict adverse peripartum outcome among high-risk parturients. Am J Obstet Gynecol. 1997;176(6):1130-8.</mixed-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <mixed-citation>Zhang J, Troendle J, Meikle S, Klebanoff MA, Rayburn WF. Isolated oligohydramnios is not associated with adverse perinatal outcomes. BJOG: Int J Obstet Gynaecol. 2004;111(3):220-5.</mixed-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <mixed-citation>Magann EF, Nolan TE, Hess LW, Martin RW, Whitworth NS, Morrison JC. Measurement of amniotic fluid volume: accuracy of ultrasonography techniques. Am J Obstet Gynecol. 1992;167(6):1533-7.</mixed-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <mixed-citation>Wladimiroff JW, Eik-Nes SH. Amniotic fluid and placental localization. Ultrasound in Obstetrics and Gynaecology: Elsevier; 2009. p. 109-20.</mixed-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <mixed-citation>Casey BM, McIntire DD, Bloom SL, Lucas MJ, Santos R, Twickler DM, et al. Pregnancy outcomes after antepartum diagnosis of oligohydramnios at or beyond 34 weeks’ gestation. Am J Obstet Gynecol. 2000;182(4):909-12.</mixed-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <mixed-citation>Golan A, Lin G, Evron S, Arieli S, Niv D, David MP. Oligohydramnios: maternal complications and fetal outcome in 145 cases. Gynecol Obstet Invest. 1994;37(2):91-5.</mixed-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <mixed-citation>Desai P, Patel P, Gupta A. Decreased amniotic fluid index in low risk pregnancy: Any significance. J Obstet Gynecol Ind. 2004;54(5):464-6.</mixed-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <mixed-citation>Wolff F, Schaefer R. Oligohydramnios--perinatal complications and diseases in mother and child. Geburt Frauenh. 1994;54(3):139-43.</mixed-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <mixed-citation>Apel-Sarid L, Levy A, Holcberg G, Sheiner E. Placental pathologies associated with intra-uterine fetal growth restriction complicated with and without oligohydramnios. Arch Gynecol Obstet. 2009;280(4):549-52.</mixed-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <mixed-citation>Chamberlain P, Manning F, Morrison I, Harman C, Lange I. Ultrasound evaluation of amniotic fluid volume: I. The relationship of marginal and decreased amniotic fluid volumes to perinatal outcome. Am J Obstet Gynecol. 1984;150(3):245-9.</mixed-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <mixed-citation>Chhabra S, Dargan R, Bawaskar R. Oligohydramnios: a potential marker for serious obstetric complications. J Obstet Gynaecol. 2007;27(7):680-3.</mixed-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <mixed-citation>Locatelli A, Vergani P, Toso L, Verderio M, Pezzullo JC, Ghidini A. Perinatal outcome associated with oligohydramnios in uncomplicated term pregnancies. Arch Gynecol Obstet. 2004;269(2):130-3.</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
