JPSIM Journal of Pakistan Society of Internal Medicine J Pak Soc Intern Med 2709-8729 2710-0804 Pakistan Society of Internal Medicine 10.70302/jpsim.v4i1.2310 jpsim.v4i1.2310 Original Research Neonatal Sepsis: Accuracy of Hematological Scoring System for Diagnosing Neonatal Sepsis Abbas Fareeha Ahmad Bushra Shabir Sadia drsadiashabir@gmail.com * Hassan Khawaja Amjad Mayo Hospital, Lahore Services Hospital, Lahore *Correspondence: Sadia Shabir (drsadiashabir@gmail.com) 13 02 2023 2023 4 1 46 50 11 11 2022 16 12 2022 Copyright © 2023 The Author(s) 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective

To find the diagnostic accuracy of hematological scoring system in early diagnosis of neonatal sepsis taking blood culture as gold standard.

 Methodology

After IRB approval, this Cross sectional study was done in the Department of Pediatric Medicine, Mayo Hospital/ KEMU Lahore, for 6 months (Apr-Oct 2018). After informed parental consent, information including age, sex and anthropometric data were recorded. The laboratory investigations were sent to laboratory of Mayo Hospital. Complete blood counts including TLC and platelets count were done using Sysmax method. Neonatal sepsis was labeled as positive or negative on hematological score system and blood cultures.

 Results

The mean age of neonates was 14.20 ± 8.09 days. There were 60(60%) male and 40(40%) female babies. Mean weight and length of these babies were 3.05 ± 0.46 kg and 51.49 ± 1.41 cm. A total of 41(41%) babies had neonatal sepsis on hematological score and 38(38%) on blood culture. The Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value and Diagnostic Accuracy was 81.58%, 85.48%, 77.50%, 88.33% and 84.00% respectively.

 Conclusion

Hematological scoring system has high diagnostic accuracy in diagnosing neonatal sepsis at earliest, taking blood culture as gold standard.

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