Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disorder with a heterogenous mode of presentation and clinical course. We present a case of a young female with an atypical presentation of SLE. A young woman with no known prior comorbidities presenting with the history of chronic diarrhea, vomiting and weight loss, followed by generalized weakness. Extensive workup was done and she was diagnosed with lupus enteritis based on history, laboratory investigations and findings on imaging. She was given pulse therapy to which she responded very well. The case describes the importance of high clinical suspicion and timely intervention as well as adds to the evidence on a rare clinical entity- lupus enteritis.