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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v4i3.2350</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v4i3.2350</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Case Report</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Weil's Disease with Severe Anemia and Jaundice in a 19 years Old Boy</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Javed</surname>
            <given-names>Salik</given-names>
          </name>
          <email>salikjaved27@gmail.com</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Muzaffar</surname>
            <given-names>Zeeshan</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ch</surname>
            <given-names>Mohsin Masud</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>King Edward Medical University/Mayo Hospital Lahore</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Salik Javed (salikjaved27@gmail.com)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2023-09-25">
        <day>25</day>
        <month>09</month>
        <year>2023</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2023</year>
      </pub-date>
      <volume>4</volume>
      <issue>3</issue>
      <fpage>244</fpage>
      <lpage>245</lpage>
      <history>
        <date date-type="received" iso-8601-date="2023-05-16">
          <day>16</day>
          <month>05</month>
          <year>2023</year>
        </date>
        <date date-type="accepted" iso-8601-date="2023-07-22">
          <day>22</day>
          <month>07</month>
          <year>2023</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2023 The Author(s)</copyright-statement>
        <copyright-year>2023</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v4i3.2350" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v4i3.2350.pdf" content-type="application/pdf"/>
      <abstract>
        <p>Weil's disease is a infection caused by the bacteria Leptospira interrogans. Most cases present as mild to moderate category and self-resolving but few are complicated with multiorgan involvement and can lead to death. We present a case of leptospirosis in a young boy of Nankana sahib who presented with haemorrhagic, hepatic and renal manifestations. The purpose of this case report is to raise awareness in physicians regarding consideration of leptospirosis in patients with hepatic and renal involvement. It also emphasizes on primary prevention in population with zoonotic exp</p>
      </abstract>
    </article-meta>
  </front>
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  <back>
    <ref-list>
      <title>References</title>
      <ref id="ref1">
        <label>1</label>
        <mixed-citation>A 23-year-old Man with Leptospirosis and Acute Abdominal Pain. Hawai'i J Medicine Public Health. 2016 Oct;75(10):291-4.</mixed-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <mixed-citation>Healthcare Workers. Leptospirosis CDC. [Updated 2021, cited 2023 Feb 10]. Available from: [https://www.cdc.gov/leptospirosis/health_care_workers/index.html]</mixed-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <mixed-citation>Brett-Major DM, Lipnick RJ. Antibiotic prophylaxis for leptospirosis. Cochrane Hepato-Biliary Group, editor. Cochrane Database Syst Rev. 2009;https://doi.wiley.com/<pub-id pub-id-type="doi">10.1002/14651858.CD007342.pub2</pub-id></mixed-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <mixed-citation>Leptospirosis: Treatment, symptoms, and types. [Updated 2022, cited 2023 Feb 10]. Available from: [https://www.medicalnewstoday.com/articles/246829]</mixed-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <mixed-citation>Trowbridge AA, Green JB, Bonnett JD, Shohet SB, Ponnappa BD, McCombs WB. Hemolytic anemia associated with leptospirosis. Morphologic and lipid studies. Am J Clin Pathol. 1981;76(4):493–8.</mixed-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <mixed-citation>Zschiedrich S, Fischer KG. Severe Weil’s syndrome complicated by hemolytic anemia. Int J Infect Dis. 2010;14(2):e181–2.</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
