JPSIM Journal of Pakistan Society of Internal Medicine J Pak Soc Intern Med 2709-8729 2710-0804 Pakistan Society of Internal Medicine 10.70302/jpsim.v4i4.2358 jpsim.v4i4.2358 Original Research Predisposing Factors in Acute Kidney Injury Patients Leading to Hemodialysis Saleem Muhammad muhammadsaleem24591@import.invalid * Butt Arsalan Ayaz Ahmed Iqbal Bilal Raza Hasan Saifuddin Adnan * Arshad Ainan ainan.arshad@aku.edu * Aga Khan University, Department of Medicine Medical College, Aga Khan University, Karchi, Pakistan University of Mississippi, USA West Virginia University, USA *Correspondence: Muhammad Saleem (muhammadsaleem24591@import.invalid); Adnan Saifuddin; Ainan Arshad (ainan.arshad@aku.edu) 29 11 2023 2023 4 4 289 292 16 08 2023 11 08 2023 Copyright © 2023 The Author(s) 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective

To identify the risk variables of AKI patients needing hemodialysis in a tertiary care hospital in Pakistan.

 Methodology

A retrospective study of 1100 patients included in the research between January 2017 and Decem-ber 2018 at Aga Khan University Hospital, of which 347 met the inclusion criteria.

 Results

According to the study, sepsis - which affects 30% of patients - emerged as the most important risk factor for needing dialysis. Dialysis was necessary for 0.7% of patients with stage 1 AKI, 7.7% of patients with stage 2 AKI, and 14.2% of patients with stage 3 AKI.

 Conclusion

According to the study, sepsis is a key risk factor for AKI requiring hemodialysis, even in cases with less severe form of AKI. These results assist in patient management and follow-up as they highlight the common risk factors that could lead to short and long- term morbidity and mortality of AKI patients. The study also implies that these results might guide focused therapy actions to improve patient outcomes.

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