JPSIM Journal of Pakistan Society of Internal Medicine J Pak Soc Intern Med 2709-8729 2710-0804 Pakistan Society of Internal Medicine 10.70302/jpsim.v5i1.2407 jpsim.v5i1.2407 Original Research Frequency of Peripheral Arterial Disease in Patients with Type-2 Diabetes Mellitus: A single center experience from a Private Healthcare Facility of South Punjab, Pakistan Masroor Maria mariamasroor@hotmail.com * Ali Qazi Masroor Shafique Sadaf Imran Ali Ullah Hafiz Muhammad Kaleem Khan Raheel Masroor Aleena Shaikh Zayed Hospital, Rahim Yar Khan AVA Serene Hospital, Bahawalpur Quaid-e-Azam Medical College, Bahawalpur Bahawal Victoria Hospital, Bahawalpur Shahida Islam Teaching Hospital and Medical College, Lodhran *Correspondence: Maria Masroor (mariamasroor@hotmail.com) 28 02 2024 2024 5 1 388 392 03 10 2023 02 12 2023 Copyright © 2024 The Author(s) 2024 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. : Ankle-Brachial Index hypertension peripheral arterial disease smoking type-2 diabetes mellitus 1 Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Res Clin Pract. 2019; 10.1016/j.diabres.2019.107843 2 Aamir AH, Ul-Haq Z, Mahar SA, Qureshi FM, Ahmad I, Jawa A, et al. Diabetes Prevalence Survey of Pakistan (DPS-PAK): prevalence of type 2 diabetes mellitus and prediabetes using HbA1c: a population-based survey from Pakistan. BMJ Open. 2019;9(2):e025300. 3 Ali QM, Anjum S, Shafique S, Hamza H, Imran A, Khan R, et.al. Risk of diabetic foot ulcer in Patients of diabetes mellitus visiting a private setting of South Punjab, Pakistan. J Pak Soc Intern Med. 2022;3(4):301-305. 4 GBD 2019 Peripheral Artery Disease Collaborators. Global burden of peripheral artery disease and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Glob Health. 2023;11(10):e1553-65. 5 Shu J, Santulli G: Update on peripheral artery disease: epidemiology and evidence-based facts. Atherosclerosis. 2018;10.1016/j.atherosclerosis.2018.05.033 6 Jelani QU, Petrov M, Martinez SC, Holmvang L, Al-Shaibi K, Alasnag M. Peripheral Arterial Disease in Women: an Overview of Risk Factor Profile, Clinical Features, and Outcomes. Curr Atheroscler Rep. 2018;20(8):40. 7 Hicks CW, Selvin E. Epidemiology of Peripheral Neuropathy and Lower Extremity Disease in Diabetes. Curr Diab Rep. 2019;19(10):86. 8 Zheng ZJ, Rosamond WD, Chambless LE, Nieto FJ, Barns RW, Hutchinson RG, et al. Lower extremity arterial disease assessed by ankle-brachial index in a middle-aged population of African Americans and whites: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Prev Med. 2005;29(5 Suppl 1):42-9. 9 Berkovitch A, Iakobishvili Z, Fuchs S, Atar S, Braver O, Eisen A, et al. Peripheral artery disease, abnormal ankle-brachial index, and prognosis in patients with acute coronary syndrome. Front Cardiovasc Med. 2022;10.3389/fcvm.2022.902615 10 Alves-Cabratosa L, Comas-Cufí M, Ponjoan A, Maria G, Ruth M, Jordi B, et al. Levels of ankle-brachial index and the risk of diabetes mellitus complications. BMJ Open Diabetes Res Care. 2020;8(1):e000977. 11 Comşa HI, Zdrenghea D, Man SC, Pop D. The role of novel atherosclerosis markers in peripheral artery disease: is there a gender difference?. Cardiovasc J Afr. 2018;29(5):322-30. 12 Naveed S, Ali Z, Nageen A, Ahmed SM, Fatima M, Zehra F. Relationship between Ankle Brachial Index (ABI) and Cardiovascular Risk Factors in Diabetes Type II. Pak Heart J 2020;53(04):337–42. 13 Cáceres-Farfán L, Moreno-Loaiza M, Cubas WS. Ankle-brachial index: more than a diagnostic test?. Arch Peru Cardiol Cir Cardiovasc. 2021;2(4):254-62. 14 da Silva FPJ, Teodoro ECM, Pereira ECA, dos Reis MVC. Prevalence of peripheral arterial disease and associated factors in people with type 2 diabetes. Fisioter Mov. 2021;10.1590/fm.2021.34122 15 Okello S, Millard A, Owori R, et al. Prevalence of lower extremity peripheral artery disease among adult diabetes patients in southwestern Uganda. BMC Cardiovasc Disord. 2014; 10.1186/1471-2261-14-75 16 Lange S, Diehm C, Darius H, Haberl R, Allenberg JR, Pittrow D, et al. High prevalence of peripheral arterial disease and low treatment rates in elderly primary care patients with diabetes. Exp Clin Endocrinol Diabetes. 2004;112(10):566-73. 17 Agarwal AK, Singh M, Arya V, Garg U, Singh VP, Jain V. Prevalence of peripheral arterial disease in type 2 diabetes mellitus and its correlation with coronary artery disease and its risk factors. J Assoc Physicians India. 2012;60(7):28-32. 18 Gregg EW, Sorlie P, Paulose-Ram R, Gu Q, Eberhardt MS, Wolz M, et al. Prevalence of lower-extremity disease in the US adult population >=40 years of age with and without diabetes: 1999-2000 national health and nutrition examination survey. Diabetes Care. 2004;27(7):1591-7. 19 Norman PE, Davis WA, Bruce DG, Davis TM. Peripheral arterial disease and risk of cardiac death in type 2 diabetes: the Fremantle Diabetes Study. Diabetes Care. 2006;29(3):575-80. 20 Selvin E, Erlinger TP. Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999-2000. Circulation. 2004;110(6):738-43. 21 Umer A, Khan KA, Naz S, Mushtaq S, Khan SN, RazaT, et al. frequency of peripheral arterial disease in high risk type 2 diabetes mellitus using ankle-brachial index and its association with the risk factors among patients presenting in jinnah hospital, lahore: Peripheral arterial disease in high risk type-2 diabetes mellitus. Pak Armed Forces Med J. 2018;68(4):761–66. 22 Akram J, Aamir A, Basit A, Qureshi MS, Mehmood T, Shahid SK, et al. Prevalence of peripheral arterial disease in type 2 diabetics in Pakistan. J Pak Med Assoc. 2011;61(7):644-648. 23 Weragoda J, Seneviratne R, Weerasinghe MC, Wijeyaratne SM. Risk factors of peripheral arterial disease: a case control study in Sri Lanka. BMC Res Notes. 2016;9(1):508. 24 Weledji EP, Alemnju NT, Nouediou C. The use of ankle brachial pressure indices in a cohort of black African diabetic patients. Ann Med Surg (Lond). 2018;10.1016/j.amsu.2018.09.009 25 Ali QM , Akram M, Imran A, Shafique S, Ullah HMK, Khan R, et al. Factors associated with poor glycemic control: A real world data from a private outpatient clinic of South Punjab, Pakistan. J Pak Soc Intern Med. 2022;3(3):210-5.