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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v5i1.2416</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v5i1.2416</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Case Report</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Amlodipine Poisoning with Transient Cardiomyopathy and Concurrent Benzodiazepine Overdose</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Akhlaq</surname>
            <given-names>Safia</given-names>
          </name>
          <email>akhlaq.safia@gmail.com</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Aziz</surname>
            <given-names>Adil</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Mahmood</surname>
            <given-names>Saad Bin Zafar</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>Aga Khan University Hospital,Karachi</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Safia Akhlaq (akhlaq.safia@gmail.com)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2024-02-28">
        <day>28</day>
        <month>02</month>
        <year>2024</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2024</year>
      </pub-date>
      <volume>5</volume>
      <issue>1</issue>
      <fpage>433</fpage>
      <lpage>435</lpage>
      <history>
        <date date-type="received" iso-8601-date="2023-10-08">
          <day>08</day>
          <month>10</month>
          <year>2023</year>
        </date>
        <date date-type="accepted" iso-8601-date="2023-12-15">
          <day>15</day>
          <month>12</month>
          <year>2023</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2024 The Author(s)</copyright-statement>
        <copyright-year>2024</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v5i1.2416" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v5i1.2416.pdf" content-type="application/pdf"/>
      <abstract>
        <sec>
          <title>Introduction</title>
          <p>A 25 year old male with an intentional ingestion of amlodipine and benzodiazepine with suicidal intention, due to peer pressure and psychological distress, had experienced transient cardiomyopathy. This case depicts the improved left ventricular function after the successful management of poisoning with a timely conventional management strategy (i.e. via intravenous fluid, vasopressor and inotropic support and Glucagon and Insulin infusion with 10% Dextrose water, and calcium gluconate administration). Amlodipine is a longer acting dihydropyridine calcium channel blocker that effectively controls blood pressure for 24 hours. It is a commonly used and safe antihypertensive agent.1 Nevertheless, the overdose can have deleterious side effects.2-4 .Physician should have high index of suspicion of amlodipine poisoning in the patient having refractory shock with the history of drug overdose. As early recognition and timely management of acute amlodipine poisoning will result in successful outcome, like in our case.</p>
        </sec>
      </abstract>
    </article-meta>
  </front>
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  <back>
    <ref-list>
      <title>References</title>
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  </back>
</article>
