JPSIM Journal of Pakistan Society of Internal Medicine J Pak Soc Intern Med 2709-8729 2710-0804 Pakistan Society of Internal Medicine 10.70302/jpsim.v5i1.2419 jpsim.v5i1.2419 STUDENT CORNER Frequency of Transaminitis in Patient with Dengue Fever in First Five Days of Illness: A Hospital Based Survey Benyamin Javeria javeriabenyamin222@gmail.com * Anwar Sidra Rauf Kamran Fatima Memorial Hospital Shadman, Lahore. *Correspondence: Javeria Benyamin (javeriabenyamin222@gmail.com) 28 02 2024 2024 5 1 441 445 14 10 2023 18 12 2023 Copyright © 2024 The Author(s) 2024 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective

To determine the frequency of transaminitis in patients with documented dengue fever in first five days of illness and their association with the disease severity.

 Methodology

A retrospective cross-sectional observational study including 382 patients with confirmed dengue serology admitted in Department of Medicine of Fatima Memorial Hospital Lahore during July 2022-July 2023. Patient demographics, presenting symptoms, clinical signs, laboratory parameters such as complete blood count (CBC) and liver function tests (LFTs) were collected and frequency of transaminitis was determined in patients correlating with disease severity in the first five days of illness. Comparisons were drawn between age groups and gender. P-value

 Results

Out of 382 patients, only 275 had reported transaminitis which is approximately 72% of total population. Significant association was found between transaminitis and severity of disease.

 Conclusion

Overall frequency of transaminitis in otherwise healthy patients (not having liver disease history) was statistically significant and accounted for almost two thirds of the dengue patients whereas one third of the patients did not have transaminitis. Statistical relationship between transaminitis and severity of disease was also noted.

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