JPSIM Journal of Pakistan Society of Internal Medicine J Pak Soc Intern Med 2709-8729 2710-0804 Pakistan Society of Internal Medicine 10.70302/jpsim.v5i2.2429 jpsim.v5i2.2429 Original Research Incidence of Culture Proven UTI and Antimicrobial Sensitivity Pattern among the Adult Population in the Local Area Asim Ammara Javed Rehman Aziz Aisha Kazi Asma docasmakazi@gmail.com * Riaz Muhammad Khan Murad Ali Zarar Faisal Arif Memorial Teaching Hospital, Rashid Latif Medical College, Lahore *Correspondence: Asma Kazi (docasmakazi@gmail.com) 07 06 2024 2024 5 2 496 501 28 01 2024 16 03 2024 Copyright © 2024 The Author(s) 2024 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective

To determine the incidence of culture proven UTI and antimicrobial sensitivity patterns among adult

population in local area of Lahore.

 Methodology

In this retrospective study, a total of 287 cases diagnosed with UTI were selected from Arif Memorial Teaching Hospital (AMTH) Lahore. Non probability sampling technique was applied and data was collected through structured questionnaire. Data for the factors associated with UTI was obtained from their respective files from the record room of AMTH. A computer software SPSS version 26.0 was used to analyze the data.

 Results

Out of 287 sample cultures, 122 samples were positive for different uropathogens. 59.0% showed E. coli strains followed by Staph. Epidermidis (10.7%), Klebsiella (8.2%), Proteus (7.4%), Enterobacter (5.7%), Pseudomonas (4.9%) and Staph Aureus (4.1%). In addition, the isolates showed multi-drug resistance. Among 122 patients, 72.1% were females and 28.7% were 27-35 years old. The risk factors among these patients were pregnancy (38.5%), followed by,

hypertension (33.6%) and diabetes (27.9%).

 Conclusion

Study concluded that UTIs were more common amongst females. Frequent use of antimicrobials without culture and sensitivities has led to emerging resistance to multiple antimicrobials to a problematic extent. Hence a urine culture and sensitivity should be advised before the initiation of antimicrobial drugs among patients with UTI.

 Keywords Urinary tract infection E. coli drug resistant antimicrobial sensitivity.