JPSIM Journal of Pakistan Society of Internal Medicine J Pak Soc Intern Med 2709-8729 2710-0804 Pakistan Society of Internal Medicine 10.70302/jpsim.v5i3.2453 jpsim.v5i3.2453 Original Research Frequency of Renal Impairment Among Patients with Liver Cirrhosis with Spontaneous Bacterial Peritonitis Hadi Muhammad Hanif Khan Muhammad Aasim asim.khan@gkmcs.edu.pk * Javeed Muhammad Khan Arshad Nawaz Asif Gajju Khan Medical College, Swabi District Specialist, District Head Quarter Hospital, Nowshera. *Correspondence: Muhammad Aasim Khan (asim.khan@gkmcs.edu.pk) 30 08 2024 2024 5 3 624 628 16 02 2024 07 08 2024 Copyright © 2024 The Author(s) 2024 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective

This study aim was to ascertain the prevalence of renal impairment among patients diagnosed with spontaneous bacterial peritonitis resulting from liver cirrhosis.

 Methodology

The descriptive cross-sectional study was conducted in the Department of Gastroenterology, Hayatabad Medical Complex, located in Peshawar. The study duration was 6 months from September 29th, 2022 to March 29th, 2022. A cohort of 212 individuals was examined to ascertain the prevalence of renal dysfunction among patients afflected with spontaneous bacterial peritonitis because of liver cirrhosis.

 Results

A total of 212 patients were recruited in which 34.3% (n=72 ) were found in aged 31-40 years. The mean age of the participants was 51.5±3.3 years. Among total, 87 (41.4%) were male and 123 (58.6%) were female patients. Among total, 48 (22.9%) were found in underweight range. It was observed that 96 patients (45.7%) had renal impairment, while 114 patients (54.3%) not affected with renal impairment. The analysis revealed that smoking was seen in 80 individuals (38.1%), whereas hypertension was observed in 120 individuals (57.1%).

 Conclusion

Renal impairment has significant prevalent occurrence among cirrhotic patients presenting with ascites and spontaneous bacterial peritonitis (SBP). The SBP-RI variable has significant predictive value for hospital mortality in individuals diagnosed with SBP. Individuals who have significantly compromised liver function or pre-existing kidney failure are more susceptible to the development of spontaneous bacterial peritonitis with renal impairment.

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