To determine the prevalence of infection with Helicobacter pylori in GERD patients and compare the incidence of

erosive esophagitis and non-erosive reflux illness in those patients.

This descriptive cross sectional was done at Medical division of Mayo Hospital Lahore from 6th Dec 2021 to

6th June 2022.Total of 150 patients fulfilling the inclusion criteria were enrolled after taking informed consent. Endoscopy

was performed in all patients. Both non-erosive reflux disease and erosive esophagitis were found endoscopically. All

patients had tissue biopsies obtained for histopathology, which were then forwarded to the pathology lab for H. pylori

detection.

Out of 150 patients, 58.7% (88) were female and 41.3% (62) were male. These patients were between the ages of

15 and 65. They were split into two groups: younger people, whose ages ranged from 15 to 40 (mean: 26.84 ± 7.478), and

middle-aged people, whose ages ranged from 41 to 65 (mean: 51.31 ± 7.378). 32% (48) of the population was in the

middle age bracket, while 68% (102) were among the young. 13.3% (20) of the patients had erosive esophagitis, while

86.7% (130) had non-erosive reflux illness. 20% (4) of patients with erosive esophagitis and 29.23% (38) of individuals

with non-erosive reflux disease had H pylori infection. (P < 0.3).

Patients with GERD are more likely to have non-erosive reflux disease than erosive esophagitis on endoscopy,

and non-erosive reflux disease is linked to a higher incidence of helicobacter infection.