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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v5i4.2477</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v5i4.2477</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Diagnostic Accuracy of CT PNS in Diagnosing Fungal Sinusitis and its Relation with Endoscopy and Histopathological Findings</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Abbasi</surname>
            <given-names>Hina Hafeez</given-names>
          </name>
          <email>hinahafeezabbasi40521@import.invalid</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Batool</surname>
            <given-names>Fizza</given-names>
          </name>
          <xref ref-type="aff" rid="aff2"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Azam</surname>
            <given-names>Madiha</given-names>
          </name>
          <xref ref-type="aff" rid="aff3"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Qadir</surname>
            <given-names>Hussnain</given-names>
          </name>
          <xref ref-type="aff" rid="aff4"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Shoaib</surname>
            <given-names>Mahwish</given-names>
          </name>
          <xref ref-type="aff" rid="aff5"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Tariq</surname>
            <given-names>Zeeshan</given-names>
          </name>
          <xref ref-type="aff" rid="aff6"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>Rawalpindi Medical University, Rawalpindi</institution>
      </aff>
      <aff id="aff2">
        <institution>Rawalpindi Teaching Hospital, Rawalpindi</institution>
      </aff>
      <aff id="aff3">
        <institution>Benazir Bhutto Hospital, Rawalpindi</institution>
      </aff>
      <aff id="aff4">
        <institution>Govt. Rural Dispensary, District Khanewal</institution>
      </aff>
      <aff id="aff5">
        <institution>Punjab Institute of Neurosciences, Lahore</institution>
      </aff>
      <aff id="aff6">
        <institution>Lahore General Hospital, Lahore</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Hina Hafeez Abbasi (hinahafeezabbasi40521@import.invalid)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2024-12-09">
        <day>09</day>
        <month>12</month>
        <year>2024</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2024</year>
      </pub-date>
      <volume>5</volume>
      <issue>4</issue>
      <fpage>745</fpage>
      <lpage>749</lpage>
      <history>
        <date date-type="received" iso-8601-date="2024-02-16">
          <day>16</day>
          <month>02</month>
          <year>2024</year>
        </date>
        <date date-type="accepted" iso-8601-date="2024-11-03">
          <day>03</day>
          <month>11</month>
          <year>2024</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2024 The Author(s)</copyright-statement>
        <copyright-year>2024</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v5i4.2477" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v5i4.2477.pdf" content-type="application/pdf"/>
      <abstract>
        <sec>
          <title>Objective</title>
          <p>To assess the diagnostic accuracy of CT PNS in diagnosing fungal sinusitis and its relation with endoscopy and</p>
          <p>histopathology</p>
        </sec>
        <sec>
          <title>Methodology</title>
          <p>This cross sectional retrospective study was conducted at Benazir Bhutto Hospital, Rawalpindi from July 2022</p>
          <p>to July 2023. Data of 153 individuals was collected who underwent CT PNS, Endoscopy and histopathology. Data was</p>
          <p>analyzed in SPSS version. 26.</p>
        </sec>
        <sec>
          <title>Results</title>
          <p>The mean age of individuals was 39.38 ± 7.05 years. Out of 153 individuals, 87 (56.9%) were males and 66</p>
          <p>(43.1%) were females. On CT PNS, out of 153 individuals, 122 (79.7%) individuals were positive for fungal sinusitis but 31</p>
          <p>(20.3%) were found negative. On histopathology, results were almost same as results obtained on CT, on histopathology</p>
          <p>i.e. 119 (77.8%) positive and 34 (22.2%) negative. Against endoscopy as well as against histopathology, CT PNS showed</p>
          <p>sensitivity and specificity of 95% and 73.5%, respectively. The overall diagnostic accuracy of CT PNS was 90.2% against</p>
          <p>endoscopy.</p>
        </sec>
        <sec>
          <title>Conclusion</title>
          <p>Thus CT PNS serves as a good diagnostic tool for detection of fungal sinusitis and a reliable guide for the</p>
          <p>surgeon, since diseases confined to the nose and paranasal sinuses may be effectively done under endoscopic techniques.</p>
        </sec>
      </abstract>
      <kwd-group xml:lang="en" kwd-group-type="author-keywords">
        <title>Keywords</title>
        <kwd>computed tomography</kwd>
        <kwd>fungal sinusitis</kwd>
        <kwd>endoscopy</kwd>
        <kwd>histopathology</kwd>
        <kwd>paranasal sinus.</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <!-- <body> omitted: no manuscript (.docx) on file -->
  <back>
    <notes notes-type="ethics-statement">
      <title>Ethics Statement</title>
      <p>Ethics committee: Institutional Research Ethics Forum, Rawalpindi Medical University, Rawalpindi, Pakistan. Approval number: 630/IREF/RMU/2024, dated 01-03-2024.</p>
    </notes>
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  </back>
</article>
