JPSIM Journal of Pakistan Society of Internal Medicine J Pak Soc Intern Med 2709-8729 2710-0804 Pakistan Society of Internal Medicine 10.70302/jpsim.v6i2.2533 jpsim.v6i2.2533 Original Research Pulmonary Function Test Abnormalities in Patients of Chronic Kidney Disease at a Tertiary Care Hospital of Lahore Ahmad Muhammad doctor.ahmad84@gmail.com * Iqbal Arslan Fatima Saba Arshad Umair Mumtaz Sami Ullah Rauf Sundus Central Park Medical College Teaching Hospital Lahore Narowal Medical College, DHQ Teaching Hospital, Narowal *Correspondence: Muhammad Ahmad (doctor.ahmad84@gmail.com) 05 06 2025 2025 6 2 175 179 14 10 2024 10 01 2025 25 04 2025 Copyright © 2025 The Author(s) 2025 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objectives

To evaluate the pulmonary function test abnormalities in patients of chronic kidney disease (CKD).

 Methodology

This prospective study was conducted at the Department of Pulmonology and Critical Care, Central Park Teaching Hospital, Lahore, from June 2023 to December 2023. A total of 61 patients were enrolled after getting an informed consent. Spirometry pulmonary function tests were done for all enrolled patients before and after hemodialysis.

 Results

Out of the total 61 patients, there were 28 male (45.9%) and 33 (54.1%) female participants with a mean age of 45.40±8.45 years. The mean FVC% of the enrolled patients before hemodialysis was 47.8 ± 27.9% and after hemodialysis was 58.2±5.2% with a statistically significant P-value. The mean FEV1% of the enrolled patients before hemodialysis was 40.24±2.37% and after hemodialysis was 48.2±4.2% with a statistically significant P-value. The mean FEV1/FVC (%) of the enrolled patients before hemodialysis was 68.0±2.70% and after hemodialysis was 81.9±1.9% with a statistically significant P-value. The mean FEF 25-75% of the enrolled patients before hemodialysis was 53.34±2.46% and after hemodialysis was 57.8±2.1% with a statistically significant P-value. The mean PEF% of the enrolled patients before hemodialysis was 46.8±3.3% and after hemodialysis was 51.7±2.7% with a statistically significant P-value.

 Conclusion

We concluded that there were significant improvements in pre- and post-hemodialysis spirometry parameters. Therefore, this study will help the clinical practitioner to consider treatment strategies keeping in mind the comorbidities in CKD patients.

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