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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPSIM</journal-id>
      <journal-title-group>
        <journal-title>Journal of Pakistan Society of Internal Medicine</journal-title>
        <abbrev-title>J Pak Soc Intern Med</abbrev-title>
      </journal-title-group>
      <issn publication-format="print">2709-8729</issn>
      <issn publication-format="electronic">2710-0804</issn>
      <publisher>
        <publisher-name>Pakistan Society of Internal Medicine</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.70302/jpsim.v7i1.2605</article-id>
      <article-id pub-id-type="publisher-id">jpsim.v7i1.2605</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Impact of Ramadan Fasting on Patients with Diabetes Type 1 Diabetes Mellitus: An Observational Study From Pakistan</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Munir</surname>
            <given-names>Atif</given-names>
          </name>
          <email>atif113_2000@yahoo.co.uk</email>
          <xref ref-type="aff" rid="aff1"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Anwer</surname>
            <given-names>Fahad</given-names>
          </name>
          <xref ref-type="aff" rid="aff2"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Hasan</surname>
            <given-names>Mohammad Imtiaz</given-names>
          </name>
          <xref ref-type="aff" rid="aff3"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Choudhry</surname>
            <given-names>Kiran S.</given-names>
          </name>
          <xref ref-type="aff" rid="aff4"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Anwar</surname>
            <given-names>Anum</given-names>
          </name>
          <xref ref-type="aff" rid="aff5"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Malik</surname>
            <given-names>Uzma</given-names>
          </name>
          <xref ref-type="aff" rid="aff6"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <institution>Fatima Memorial College of Medicine and Dentistry. Lahore, Pakistan</institution>
      </aff>
      <aff id="aff2">
        <institution>King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia</institution>
      </aff>
      <aff id="aff3">
        <institution>Diabetes Institute Pakistan Lahore, Pakistan</institution>
      </aff>
      <aff id="aff4">
        <institution>Shalamar Hospital, Lahore, Pakistan</institution>
      </aff>
      <aff id="aff5">
        <institution>Meethi Zindagi, Lahore, Pakistan</institution>
      </aff>
      <aff id="aff6">
        <institution>King Edward medical University, Lahore, Pakistan.</institution>
      </aff>
      <author-notes>
        <corresp id="cor1">*Correspondence: Atif Munir (atif113_2000@yahoo.co.uk)</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic" iso-8601-date="2026-03-10">
        <day>10</day>
        <month>03</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2026</year>
      </pub-date>
      <volume>7</volume>
      <issue>1</issue>
      <fpage>22</fpage>
      <lpage>27</lpage>
      <history>
        <date date-type="received" iso-8601-date="2025-07-17">
          <day>17</day>
          <month>07</month>
          <year>2025</year>
        </date>
        <date date-type="rev-recd" iso-8601-date="2026-01-05">
          <day>05</day>
          <month>01</month>
          <year>2026</year>
        </date>
        <date date-type="accepted" iso-8601-date="2026-02-17">
          <day>17</day>
          <month>02</month>
          <year>2026</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright © 2026 The Author(s)</copyright-statement>
        <copyright-year>2026</copyright-year>
        <copyright-holder>The Author(s)</copyright-holder>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v7i1.2605" content-type="text/html"/>
      <self-uri xlink:href="https://psimj.com/article/jpsim.v7i1.2605.pdf" content-type="application/pdf"/>
      <abstract>
        <sec>
          <title>Objective</title>
          <p>This study assessed the impact of pre-Ramadan medical assessment, education, and individualized insulin adjustments on diabetes-related complications in fasting T1DM patients under medical supervision.</p>
        </sec>
        <sec>
          <title>Methodology</title>
          <p>A prospective observational study was conducted at Fatima Memorial Hospital, Lahore, involving 28 T1DM patients (82.1% aged ≥20 years, 67.9% female). Participants underwent pre-Ramadan risk stratification (IDF-DAR guidelines), structured education, and insulin regimen optimization. During Ramadan, remote monitoring via WhatsApp provided real-time support. Outcomes included hypoglycemia, hyperglycemia, DKA, and hospitalization rates.</p>
        </sec>
        <sec>
          <title>Results</title>
          <p>Younger participants (20 days, with 11.3% completing all fasts. Frequent glucose self-monitoring was associated with better outcomes (*p*=0.03 for females).</p>
        </sec>
        <sec>
          <title>Conclusion</title>
          <p>Pre-Ramadan assessment, education, and remote supervision enable safer fasting in low-to-intermediate- risk T1DM patients. Younger individuals and those with poorer glycemic control require closer monitoring. Structured interventions mitigate acute complications, though larger studies are needed to refine guidelines.</p>
        </sec>
      </abstract>
      <kwd-group xml:lang="en" kwd-group-type="author-keywords">
        <title>Keywords</title>
        <kwd>Ramadan fasting</kwd>
        <kwd>Type 1 diabetes</kwd>
        <kwd>hypoglycemia</kwd>
        <kwd>insulin adjustment</kwd>
        <kwd>Pakistan.</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <!-- <body> omitted: no manuscript (.docx) on file -->
  <back>
    <notes notes-type="ethics-statement">
      <title>Ethics Statement</title>
      <p>Ethics committee: Institutional Review Board, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore, Pakistan. Approval number: FMH-21/3/2023-IRB-1192, dated April 26, 2023.</p>
    </notes>
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  </back>
</article>
