Impact of Acute Kidney Injury on In-Hospital Outcomes Amongst Critically Ill Patients
AbstractObjective: Present research was conducted study to determine frequency of acute kidney injury in intensive care unit and its impact on duration of stay and mortality.
MethodsPatients aged ≥12 years having normal serum creatinine on admission were consecutively enrolled. Exclusion criteria included chronic kidney disease, unwilling patients and those developing acute kidney injury outside intensive care unit. Urine output and serum creatinine were monitored daily to detect acute kidney injury using KDIGO criteria. Duration of in hospital stay and intensive care unit, need for mechanical ventilation and in-hospital mortality were compared amongst patients with and without acute kidney injury.
Results 163 patients aged 53.67±21.69 years were enrolled of which 27 (16.56%) developed acute kidney injury, 13 (7.98%) required hemodialysis, 26 (15.95%) required mechanical ventilation and 37(22.70%) died. Patients with acute kidney injury stay longer in intensive care unit as compared to those not developing it (median 5 vs 2 days, p=0.013). Same was the case with total stay in hospital (median 11 vs 8 days, p=0.044). Acute kidney injury did not influence need for mechanical ventilation (14.81% vs 16.18%, p=1.000) or mortality (29.63% vs 21.32%, p=0.347)
Conclusion Patients with Acute kidney injury stayed longer in intensive care unit but it does not affect mortality or need for mechanical ventilation.
Keywords:critical care, hospitalization, intensive care unit, outcome assessment, renal dialysis, renal replacement therapy
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