Assessment of Efficacy and Safety of Ivermectin in the Patients of COVID-19


  • Author- Atif Mahmood, Asma Khan, Ayesha Shahbaz, Saira Pervaiz


Objective: Primary objective of the study is to evaluate the efficacy and safety of ivermectin in reducing the progression and severity of Covid-19. Secondary objective of the study is to compare viral clearance rate among the study group and evaluation of side effects of therapy.


This cross-sectional observational study was undertaken at Department of Pulmonology Fatima Memorial Hospital, Lahore.After taking a medical history and doing a physical examination, oral ivermectin(12 mg once daily for 5 days) was given to 350 patients with COVID-19. Throughout treatment, the clinical efficacy of ivermectin, viral clearance rate, and adverse effects of medication were assessed and recorded on a prepared Performa.


 Ivermectin therapy demonstrated 99.9 percent efficacy in patients treated with it. The paired sample t test revealed statistically significant differences in radiographic findings and PCR laboratory examination prior to and following ivermectin administration. While all clinical symptoms improved following medication. On the other hand, 2 persons (4%) have reported experiencing adverse effects from the medicine.


 Ivermectin induction has been presented as a more successful technique for treating Covid-19 infection


Ivermectin, Covid-19, anti-helmenthic