Absolute Neutrophil Count and Thrombocytopenia in Patients ofAcute Dengue Infection


  • Author- Rafia Behzad, Sehar Khaliq, Rafiq Ahmed Shahid


Objective: To determine mean Absolute Neutrophil Count and frequency of thrombocytopenia in patients of acute dengue infection.


: This descriptive cross sectional study was done in Hematology Department, Medical and Pediatric wards, Fauji Foundation Hospital, Rawalpindi. A total of 100 patients diagnosed as a case of acute dengue infection based on Indirect ELISA for anti DENV IgM were selected using inclusion and exclusion criteria. Venous blood of 2.5 ml of these patients was collected in CPbottle containing EDTAas anticoagulant. It was analyzed on automated Hematology analyzer Sysmex XT 2000i system. Blood levels of Absolute Neutrophil Count and platelet count were recorded and documented for these patients.


 : Out of 100 diagnosed patients of acute dengue infection, 81% exhibited thrombocytopenia, while the mean absolute neutrophil count calculated in these patients was 1.96 x 109 /L.


 :Acute dengue fever is characterized by thrombocytopenia and neutropenia. Therefore, in a patient with signs and symptoms of acute febrile illness, a blood count analysis is imperative in assisting earlier diagnosis of dengue fever.


: Acutedengue infection,CompleteBloodCount(CBC),AbsoluteNeutrophilCount(ANC),Thrombocytopenia.