Frequency of Gastroesophageal Variceal Bleeding In Cirrhotic Patients with and without Diabetes
MethodsIt was a cross-sectional study, conducted at Department of Medicine Unit-III, Services Hospital, Lahore from 22/12/2016 to 21/06/2017. This study involved 134 patients of both genders aged between 25-65 years diagnosed of cirrhosis at least a year ago. These patients were assessed for the presence of diabetes and gastroesophageal variceal bleed. Frequency of GEVB was compared among cirrhotic patients with and without diabetes.
Results  Mean age of the patients was 53.51±8.53 years, and majority were aged between 51-65 years (61.2%) and 35-50 years (38.8%). There were 80 (59.7%) male and 54 (40.3%) female patients in the study group with a male to female ratio of 1.5:1. The mean duration of cirrhosis was 23.73±10.24 months. 48 (35.8%) patients had Hepatitis B while 86 (64.2%) patients had Hepatitis C on viral serology. Diabetes was diagnosed in 46 (34.3%) patients with cirrhosis. We observed no significant difference in the frequency of diabetes according to age (p=0.751), gender (p=0.842), duration of disease (p=0.864) and serological (p=0.856) groups. Gastroesophageal variceal bleeding was seen in 20 (14.9%) patients with significantly high frequency with diabetes (28.3% vs. 8.0%; p=0.002) as compared to without. Similar significant difference was observed across all age, gender, duration of disease and serological groups.
Conclusion  The frequency of diabetes was 34.3% among cirrhotic patients and of gastroesophageal variceal bleeding was significantly higher among them with diabetes (28.3% vs. 8.0%; p=0.002) as compared to those without regardless of age, gender, duration of cirrhosis and viral serology.
Keywords:Cirrhosis, Diabetes, Gastroesophageal Variceal Bleeding
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