STUDENT CORNER

Frequency and Outcome of Adverse Events in Hospitalized and Critically ill Patients

Areeba Memon1
Aga Khan Medical College, Karachi – Pakistan
Ainan Arshad1
Aga Khan Medical College, Karachi – Pakistan
Rehab Naeem1
Aga Khan Medical College, Karachi – Pakistan
Ahmed Ayaz1
Aga Khan Medical College, Karachi – Pakistan
Abbas Raza
Kamran Pasha2
Aga Khan University Hospital, Karachi – Pakistan

✉ Correspondence: Ainan Arshad Email: ainan_arshad@hotmail.com

DOI https://doi.org/10.70302/jpsim.v1i1.2018
Volume: 1, Issue 1 Pages: 78–83 Published: 16 Dec 2020
Received: 05 Sep 2020 Accepted: 12 Oct 2020 Published Online: 16 Dec 2020

Abstract

Objectives
To identify Frequency and outcome of adverse events in hospitalized critically ill patients
Methods
This is a retrospective case-control study of critically ill ICU patients was conducted from January-December 2019 at the Aga Khan University Hospital (AKUH) in Pakistan. Data was collected from patients’ medical records using a pre-approved pro forma. Variables included demographics, patient and hospitalization characteristics and laboratory investigations. Any adverse event during the admission was also noted. Outcome measures included in-hospital mortality and length of stay.
Results
773 patients met the inclusion criteria and were included in the study; 504 (65.2%) were males and 269 (34.8%) females; mean age was 57.3 ± 16.6 years. Overall mortality rate was 33%. The most common adverse events during a patients hospital stay were acute kidney injury (22%), shock (18%) and electrolyte imbalance (18%). Risk factors for mortality in these patients included mechanical ventilation, septic shock, acute kidney injury, thrombocytopenia, seizures, acute liver failure, ARDS and metabolic acidosis.
Conclusion
Our study reveals a high mortality rate for critically ill ICU patients. Adverse events during admission were frequent and also associated with increased mortality. We hope this study sets the stage for larger scale studies in developing countries to drive improvements in accurate risk stratification and optimal patient management.

Keywords
Critical care ICU shock outcome

How to Cite This Article

Memon A, Arshad A, Naeem R, Ayaz A, Raza A, Pasha K. Frequency and Outcome of Adverse Events in Hospitalized and Critically ill Patients. J Pak Soc Intern Med. 2020;1(1):78–83. doi:10.70302/jpsim.v1i1.2018

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2020 Journal of Pakistan Society of Internal Medicine.
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