Original Research

Co-Relation Between Glycated Hemoglobin (HbA1c) and Dyslipidemia in Type II Diabetics Presenting in a Tertiary Care Hospital in Pakistan

Hassan Ur Rehman
Department of Internal Medicine PIMS Islamabad.

✉ Correspondence: Hassan Ur Rehman Email: drrehman.hassan@gmail.com

DOI https://doi.org/10.70302/jpsim.v2i3.2154
Volume: 2, Issue 3 Pages: 236–240 Published: 20 Sep 2021
Received: 03 Jul 2021 Accepted: 17 Jul 2021 Published Online: 20 Sep 2021

Abstract

Objective

Diabetes is a global disease that is affecting both developing and developed countries. According to a WHO
survey (1994-1998), the overall prevalence of diabetes Mellitus is 11.47% in Pakistan. Based on a study done in Pakistan
in 2015, the prevalence of dyslipidemia among people with diabetes was 95%. Both HbA1c and dyslipidemia lead to an
increased risk for cardiovascular diseases. This study aims to identify the atherosclerotic disease risk factors among the
Pakistani population to decrease morbidity and mortality. To determine the frequency of dyslipidemia among Type 2
Diabetic patients and compare dyslipidemia among Type 2 Diabetic patients with/without elevated Glycated hemoglobin
(HbA1c).

Methods

A descriptive, cross-sectional study was performed at Internal Medicine Department, Pakistan Institute of
Medical Sciences, Islamabad, Pakistan, for Six months (Feb 02, 2020, till Jul 01, 2020). HbA1c levels, serum lipid profile,
random and fasting blood sugar levels were tested. Non-probability consecutive sampling was done, and 100 patients were
registered.

Results

Out of 100 patients, 47 were males and 53 females with a mean age of 47.85 ± 8.61. Sixty-nine diabetic patients
with elevated HbA1c showed a positive relationship with total cholesterol and LDL-C level (p<0.05). In addition, patients
with HbA1c higher than 7% showed a high risk and borderline dyslipidemia.

Conclusion

Elevated HbA1c, apart from being a glycemic index, is a good predictor of dyslipidemia. Therefore, patients
with borderline or desirable lipid profile values with high HbA1c levels should start statin therapy or lifestyle modification
to prevent cardiovascular diseases.

Keywords
Diabetes mellitus Dyslipidemia High Glycated Hemoglobin uncontrolled diabetes.

How to Cite This Article

Rehman HU. Co-Relation Between Glycated Hemoglobin (HbA1c) and Dyslipidemia in Type II Diabetics Presenting in a Tertiary Care Hospital in Pakistan. J Pak Soc Intern Med. 2021;2(3):236–240. doi:10.70302/jpsim.v2i3.2154

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2021 Journal of Pakistan Society of Internal Medicine.
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