Review Article

Dengue Fever

Somia Iqtadar1
King Edward Medical University, Lahore
Sidrah Lodhi2
Department of Medicine, King Edward Medical University, Lahore
Nabeel Akbar Chaudhary2
Department of Medicine, King Edward Medical University, Lahore
Samiullah Mumtaz2
Department of Medicine, King Edward Medical University, Lahore
Sajid Abaidullah2
Department of Medicine, King Edward Medical University, Lahore

✉ Correspondence: Somia Iqtadar Email: somia.iqtadar@gmil.com

DOI https://doi.org/10.70302/jpsim.v2i4.2165
Volume: 2, Issue 4 Pages: 293–298 Published: 14 Dec 2021
Received: 19 Sep 2021 Accepted: 23 Sep 2021 Published Online: 14 Dec 2021

Abstract

Dengue infection is Aedes mosquito-borne infectious disease of the tropics caused by dengue virus (DENV). DENV has four distinct serotypes; 1, 2, 3 and 4. Infection by each serovar confers life-long protective immunity to that and partial and transient protection against the other serotypes. Secondary infection is a major risk factor for DHF, mainly due to antibody induced enhancement.1,2 According to WHO estimates, this disease of the tropics and sub-tropics, affects around 390 million people each year and 3.9 billion people residing in 128 countries are at risk. (WHO 2017).
Dengue in history dates back to 3rd century Chinese literature of Jin Dynasty era and the first confirmed case was reported by Benjamin Rush in 1789. (www.denguevirusnet.com) Dengue has emerged as a disease with significant morbidity and mortality. After several epidemics since 2005, it is now recognized as an important health problem in Pakistan. The incidence is highest for the age group 20 to 30 years (32.0%) with females representing 31.5%. The disease has an overall case fatality rate of 1.86/ 1000 confirmed cases. It is a notifiable disease under the 3 epidemiological categories; suspected, probable and confirmed dengue.

How to Cite This Article

Iqtadar S, Lodhi S, Chaudhary NA, Mumtaz S, Abaidullah S. Dengue Fever. J Pak Soc Intern Med. 2021;2(4):293–298. doi:10.70302/jpsim.v2i4.2165

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2021 Journal of Pakistan Society of Internal Medicine.
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