Original Research

Diagnostic Accuracy of Ultrasononography in Detection for Diagnosis of Malignancy of Lymph Nodes in Newly Diagnosed Head and Neck Carcinoma Patients Taking Histopathology as Gold Standard

Abdul Qadeer Khan
Jinnah Hospital Lahore
Hafsa Iqbal
Jinnah Hospital Lahore

✉ Correspondence: Abdul Qadeer Khan Email: abdullah.qadeer1@gmail.com

DOI https://doi.org/10.70302/jpsim.v3i2.2224
Volume: 3, Issue 2 Pages: 124–128 Published: 15 Jun 2022
Received: 02 Jan 2022 Accepted: 06 Apr 2022 Published Online: 15 Jun 2022

Abstract

Objective

To determine the diagnostic accuracy of ultrasonography for diagnosis of malignancy of lymph node in newly diagnosed head and neck carcinomas patients, taking histopathology as gold standard.

Methods

This cross-sectional study was undertaken in Department of Radiology, Jinnah Hospital, Lahore. Total 168 newly diagnosed cases with head and neck carcinoma, 20-80 years of age of both genders were selected. All the patients with history of previous neck surgery, on chemotherapy or any other oncology treatment and recurrent cases were excluded. After taking informed consent, ultrasonography of neck was performed. Each USG findings were interpreted by one consultant radiologist and were looked for malignant lymph nodes as per-operational definition. USG findings were compared with histopathology findings.

Results

Age range in this study was from 20-80 years with mean age of 50.33 ± 11.98 years. Majority of the patients 92 (54.76%) were between 20-50 years of age. Out of these 168 patients, 98 (58.33%) were males and 70 (41.67%) were females with ratio of 1.4:1. All the patients were subjected to USG and found that 83 were True Positive and 08 were False Positive. Among 77, USG negative patients, 07 (False Negative) had malignant lymph nodes on histopathology whereas 70 (True Negative) had benign lymph nodes on histopathology (p=0.0001). Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of ultrasonography for diagnosis of malignancy of lymph node in newly diagnosed head and neck carcinomas patients was 92.22%, 89.74%, 91.21%, 90.91% and 91.07% respectively.

Conclusion

This study concluded that ultrasound is a highly sensitive and accurate non-invasive modality for detecting malignant lymph node in head and neck cancers.

Keywords
head and neck cancers lymph node metastasis ultrasound.

How to Cite This Article

Khan AQ, Iqbal H. Diagnostic Accuracy of Ultrasononography in Detection for Diagnosis of Malignancy of Lymph Nodes in Newly Diagnosed Head and Neck Carcinoma Patients Taking Histopathology as Gold Standard. J Pak Soc Intern Med. 2022;3(2):124–128. doi:10.70302/jpsim.v3i2.2224

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2022 Journal of Pakistan Society of Internal Medicine.
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