Original Research

Comparative Study of Postoperative Pain in Laparoscopic Cholecystectomy with and without Preoperative Intravenous Dexamethasone

Arslan Hamid1
CMH Sialkot
Misbah Iqbal2
Jinnah Hospital Lahore
Muhammad Irfan Fazal3
Mayo Hospital Lahore
M Hassan3
Mayo Hospital Lahore
Farhan Ali3
Mayo Hospital Lahore
Abrar Ashraf Ali3
Mayo Hospital Lahore

✉ Correspondence: Arslan Hamid Email: drarslanhameed@gmail.com

DOI https://doi.org/10.70302/jpsim.v3i2.2227
Volume: 3, Issue 2 Pages: 140–144 Published: 15 Jun 2022
Received: 31 Dec 2021 Accepted: 16 Apr 2022 Published Online: 15 Jun 2022

Abstract

Objective

The objective of this study was to associate mean postoperative pain score in cases undergoing laparoscopic cholecystectomy with and without preoperative intravenous dexamethasone.

Methods

This randomized controlled trial study was done at department of South Surgery, Mayo Hospital Lahore. In this study all 80 cases were taken after receiving permission from hospital ethical committee and taking well-versed consent. Using lottery method, cases were arbitrarily distributed into 2 groups, group-A and group-B. Same antibiotic for prophylaxis was given to all patients half to one hour before surgery. Group-A was given 2ml Normal Saline IV and cases selected in group-B were given dexamethasone of 8mg IV at time of induction of anesthesia. Postoperative Pain Score was noted at 6th hour of postoperative period with the help of Visual analogue Scale (VAS) as per operational definition.

Results

The mean age of cases in normal saline and dexamethasone group was 42.32 ± 15.44 years and 41.35 ± 14.24 years respectively. The minimum and maximum and maximum age in normal saline group was 18 and 65 while in dexamethasone group was 18 and 63 years. In normal saline group there were 9(22.5%) male and 31(77.5%) female cases while in dexamethasone group there were 8(20%) male and 32(80%) female cases. The mean postoperative pain score at 6th hour was 4.50 ± 1.66 in normal saline group and in dexamethasone group was 2.68 ± 0.69 with statistically lower mean pain in dexamethasone group, p-value < 0.05.

Conclusion

Through the findings of this study it is concluded that the mean pain score after surgery at 6th hour was statistically lesser in dexamethasone group. So, in future by giving injection dexamethasone we can reduce the post operative analgesia and hospital stay by early discharging the cases.

Keywords
Laparoscopy Cholecystectomy dexamethasone

How to Cite This Article

Hamid A, Iqbal M, Fazal MI, Hassan M, Ali F, Ali AA. Comparative Study of Postoperative Pain in Laparoscopic Cholecystectomy with and without Preoperative Intravenous Dexamethasone. J Pak Soc Intern Med. 2022;3(2):140–144. doi:10.70302/jpsim.v3i2.2227

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2022 Journal of Pakistan Society of Internal Medicine.
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