Ethylene Glycol Toxicity Following Brake Oil Ingestion
Abstract
Break oil is used as a lubricant in automobiles. Children and predisposed individuals with a history of mental illness are particularly at risk of intoxication. The wide range of toxic doses and delay in onset made it difficult to categorise the severity of intoxication at presentation. A 17-years-old boy presented to emergency department with excruciating abdominal pain. He was drowsy had a GCS of 12/15 and had been anuric for the previous 24hrs. The Patient disclosed that he ingested about 50ml of break oil as a suicidal attempt. Labs revealed severe metabolic acidosis with acute kidney injury at presentation. Due to late presentation and severe metabolic acidosis with kidney injury, immediate hemodialysis was planned. Three sessions of hemodialysis yielded considerable improvement over course of 3 days but patient died due to cardio toxicity on 4th day of treatment. Break oil poisoning has several clinical evolutions through the deposition of harmful metabolites. After intoxication patient can present in any phase of toxicity. Cardiopulmonary involvement and delayed treatment could be fatal as seen in this case. Early treatment of metabolic acidosis should be done to prevent vital organs from toxicity
How to Cite This Article
Khan M, Ahmad T, Khan N, Saifuddin S. Ethylene Glycol Toxicity Following Brake Oil Ingestion. J Pak Soc Intern Med. 2022;3(4):345–348. doi:10.70302/jpsim.v3i4.2269
Conflict of Interest
All authors declare no competing interests.
Funding
No specific funding was received for this research.
Funder information follows the Crossref Funder Registry standard.
References
- Tennant I, Crawford-Sykes A, Ward L, Thesiger C. Ethylene glycol poisoning following ingestion of brake fluid. West Indian Med J. 2006;55(4):286-7
- Basnayake BM, Wazil AW, Nanayakkara N, Mahanama RM, Premathilake PN, Galkaduwa KK. Ethylene glycol intoxication following brake fluid ingestion complicated with unilateral facial nerve palsy: a case report. Journal of medical case reports. 2019;13(1):1-4
- Hess R, Bartels MJ, Pottenger LH. Ethylene glycol: an estimate of tolerable levels of exposure based on a review of animal and human data. Arch Toxicol. 2004;78(12):671-80
- Tanasescu A, Macovei RA, Tudosie M. Outcome of patients in acute poisoning with ethylene glycol-factors which may have influence on evolution. J Med Life. 2014;7(Iss 3):81.
- Vadysinghe AN, Kumarasinghe WG, Kodikara S, Wickramasinghe N. Suicide by ethylene glycol/brake oil poisoning—a case report. Egyptian journal of forensic sciences. 2021;11(1):1-5.
- Kumaran SS, Chandrasekaran VP, Balaji S, Muralidharan K, Srinivas M. The ‘Sweet killer’-brake oil poisoning. Int J Med Toxicol Legal Med. 2011;13(3):49-52.
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