Original Research

Outcomes in Critical COVID 19 Infection Affected by Pre-Existing Diabetes Mellitus

Bilal Saeed
Department of Nephrology, Pak Emirates Military Hospital Rawalpindi
Abdul Rehman Arshad
Department of Nephrology, Pak Emirates Military Hospital Rawalpindi
Hafiz Muhammad Yasir Rehman
Department of Nephrology, Pak Emirates Military Hospital Rawalpindi

✉ Correspondence: Bilal Saeed Email: ayubian2019@gmail.com

DOI https://doi.org/10.70302/jpsim.v4i1.2305
Volume: 4, Issue 1 Pages: 20–23 Published: 13 Feb 2023
Received: 13 Nov 2022 Accepted: 29 Nov 2022 Published Online: 13 Feb 2023

Abstract

Objective

To determine the effect of pre-existing diabetes mellitus on disease course in COVID-19 infection.

Methods

This retrospective observational study was done from Jan 2021 to August 2021. We included patients with COVID-19 infection having a positive PCR for SARS-CoV-2. Exclusion criteria included missing data or a negative PCR for SARS-CoV-2. Patients were selected using consecutive sampling. Length of stay and death within hospital were compared amongst diabetic and non- diabetic patients.

Results

The 279 patients were aged 52.53± 11.31 years. Of these, 216 (77.42%) were males and 92 (32.97%) had diabetes. They remained admitted for 10.18± 3.13 days. The period of hospitalization was similar in diabetics and non- diabetics (10.70± 3.51 days vs 9.92± 2.91 days; p=0.052). Amongst the diabetics, 43(46.74%) died in hospital in comparison with 53 (39.55%) non- diabetics (p=0.002). The risk of in-hospital death in diabetics was 1.673 (95% CI 1.207 - 2.319).

Conclusion

Diabetes mellitus is linked with greater risk of death, longer duration of hospital stay and higher need for critical care and novel therapy in COVID-19 infection.

Keywords
hospital stay mortality pandemic pneumonia

How to Cite This Article

Saeed B, Arshad AR, Rehman HMY. Outcomes in Critical COVID 19 Infection Affected by Pre-Existing Diabetes Mellitus. J Pak Soc Intern Med. 2023;4(1):20–23. doi:10.70302/jpsim.v4i1.2305

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2023 Journal of Pakistan Society of Internal Medicine.
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