Original Research

Impact of Acute Kidney Injury on In-Hospital Outcomes Amongst Critically Ill Patients

Huma Gul
Combined Military Hospital Peshawar
Abdul Rehman Arshad
Combined Military Hospital Peshawar
Haider Ali Khan
Combined Military Hospital Peshawar
Muhammad Mubasher Ijaz
Combined Military Hospital Peshawar

✉ Correspondence: Huma Gul Email: humagulaly@gmail.com

DOI https://doi.org/10.70302/jpsim.v4i1.2306
Volume: 4, Issue 1 Pages: 24–28 Published: 13 Feb 2023
Received: 26 Oct 2022 Accepted: 24 Nov 2022 Published Online: 13 Feb 2023

Abstract

Objective

Present research was conducted study to determine frequency of acute kidney injury in intensive care unit and its impact on duration of stay and mortality.

Methods

Patients aged ≥12 years having normal serum creatinine on admission were consecutively enrolled. Exclusion criteria included chronic kidney disease, unwilling patients and those developing acute kidney injury outside intensive care unit. Urine output and serum creatinine were monitored daily to detect acute kidney injury using KDIGO criteria. Duration of in hospital stay and intensive care unit, need for mechanical ventilation and in-hospital mortality were compared amongst patients with and without acute kidney injury.

Results

163 patients aged 53.67±21.69 years were enrolled of which 27 (16.56%) developed acute kidney injury, 13 (7.98%) required hemodialysis, 26 (15.95%) required mechanical ventilation and 37(22.70%) died. Patients with acute kidney injury stay longer in intensive care unit as compared to those not developing it (median 5 vs 2 days, p=0.013). Same was the case with total stay in hospital (median 11 vs 8 days, p=0.044). Acute kidney injury did not influence need for mechanical ventilation (14.81% vs 16.18%, p=1.000) or mortality (29.63% vs 21.32%, p=0.347).

Conclusion

Patients with Acute kidney injury stayed longer in intensive care unit but it does not affect mortality or need for mechanical ventilation.

Keywords
critical care hospitalization intensive care unit outcome assessment renal dialysis renal replacement therapy

How to Cite This Article

Gul H, Arshad AR, Khan HA, Ijaz MM. Impact of Acute Kidney Injury on In-Hospital Outcomes Amongst Critically Ill Patients. J Pak Soc Intern Med. 2023;4(1):24–28. doi:10.70302/jpsim.v4i1.2306

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2023 Journal of Pakistan Society of Internal Medicine.
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