Original Research

Assessment of Efficacy and Safety of Ivermectin in the Patients of COVID-19

Atif Mahmood
Department of Pulmonology Fatima Memorial Hospital,Lahore
Asma Khan
Department of Pulmonology Fatima Memorial Hospital,Lahore
Ayesha Shahbaz
Department of Pulmonology Fatima Memorial Hospital,Lahore
Saira Pervaiz
Department of Pulmonology Fatima Memorial Hospital,Lahore

✉ Correspondence: Asma Khan Email: afzal.a3s3@gmail.com

DOI https://doi.org/10.70302/jpsim.v4i3.2341
Volume: 4, Issue 3 Pages: 206–209 Published: 25 Sep 2023
Received: 17 May 2023 Accepted: 08 Jul 2023 Published Online: 25 Sep 2023

Abstract

Objective

Primary objective of the study is to evaluate the efficacy and safety of ivermectin in reducing the progression and severity of Covid-19. Secondary objective of the study is to compare viral clearance rate among the study group and evaluation of side effects of therapy.

Methods

This cross-sectional observational study was undertaken at Department of Pulmonology Fatima Memorial Hospital, Lahore. After taking a medical history and doing a physical examination, oral ivermectin(12 mg once daily for 5 days) was given to 350 patients with COVID-19. Throughout treatment, the clinical efficacy of ivermectin, viral clearance rate, and adverse effects of medication were assessed and recorded on a prepared Performa.

Results

Ivermectin therapy demonstrated 99.9 percent efficacy in patients treated with it. The paired sample t test revealed statistically significant differences in radiographic findings and PCR laboratory examination prior to and following ivermectin administration. While all clinical symptoms improved following medication. On the other hand, 2 persons (4%) have reported experiencing adverse effects from the medicine.

Conclusion

Ivermectin induction has been presented as a more successful technique for treating Covid-19 infection.

Keywords
Ivermectin Covid-19 anti-helmenthic

How to Cite This Article

Mahmood A, Khan A, Shahbaz A, Pervaiz S. Assessment of Efficacy and Safety of Ivermectin in the Patients of COVID-19. J Pak Soc Intern Med. 2023;4(3):206–209. doi:10.70302/jpsim.v4i3.2341

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2023 Journal of Pakistan Society of Internal Medicine.
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