Case Report

Hypoplastic Left Heart Syndrome

Asra Mariam1
Bahawal Victoria Hospital Bahawalpur
Zaeem Ahmad2
Mayo Hospital Lahore
Arif Hussain1
Bahawal Victoria Hospital Bahawalpur
Nouman Nazeer
Humaira Zia3
Holy Family Hospital Rawalpindi

✉ Correspondence: Zaeem Ahmad Email: zaeem.ahmad344@gmail.com

DOI https://doi.org/10.70302/jpsim.v4i3.2349
Volume: 4, Issue 3 Pages: 240–243 Published: 25 Sep 2023
Received: 08 May 2023 Accepted: 20 Jun 2023 Published Online: 25 Sep 2023

Abstract

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease characterized by varying degrees of underdevelopment of the heart's left side; this results in affected blood flow from the left half of the heart to the body. We report a case of three months old girl who presented to the outpatient department with symptoms of respiratory distress and cyanosis and was diagnosed as a case of HLHS on echocardiography. We discuss the epidemiology, clinical presentation, pathophysiology, risk factors, investigations and management of HLHS in brief.

How to Cite This Article

Mariam A, Ahmad Z, Hussain A, Nazeer N, Zia H. Hypoplastic Left Heart Syndrome. J Pak Soc Intern Med. 2023;4(3):240–243. doi:10.70302/jpsim.v4i3.2349

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

  1. Grossfeld P, Nie S, Lin L, Wang L, Anderson R: Hypoplastic Left Heart Syndrome: A New Paradigm for an Old Disease? J Cardiovasc Dev Dis. 2019; doi:10.3390/jcdd6010010 doi:10.3390/jcdd6010010
  2. Yabrodi M, Mastropietro CW: Hypoplastic left heart syndrome: from comfort care to long-term survival. Pediatr Res. 2017, 81:142–9. 10.1038/pr.2016.194 doi:10.1038/pr.2016.194
  3. Barron DJ, Kilby MD, Davies B, Wright JG, Jones TJ, Brawn WJ. Hypoplastic left heart syndrome. 2009; p. 374.
  4. Graupner O, Enzensberger C, Axt-Fliedner R: New Aspects in the Diagnosis and Therapy of Fetal Hypoplastic Left Heart Syndrome. Geburtshilfe Frauenheilkd. 2019;79(4):863-72. 10.1055/a-0828-7968 doi:10.1055/a-0828-7968
  5. Kritzmire S, Cossu A: Hypoplastic Left Heart Syndrome. Treasure Island (FL): StatPearls Publishing; 2022. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK554576/].
  6. Gobergs R, Salputra E, Lubaua I: Hypoplastic left heart syndrome: a review. Acta medica Lituanica. 2016;23(2):86.
  7. Bailey LL: Transplantation is the best treatment for hypoplastic left heart syndrome. Cardiol Young. 2004, 14(1):109–11.
  8. Fruitman DS: Hypoplastic left heart syndrome: Prognosis and management options. Paediatr Child Health. 2000, 5(2):219–25.
  9. Ohye RG, Schranz D, D’Udekem Y: Current Therapy for Hypoplastic Left Heart Syndrome and Related Single Ventricle Lesions. Circulation. 2016, 134(6):1265–79.
  10. Norwood WI: Hypoplastic left heart syndrome. Ann Thorac Surg. 1991;52(3):688-95.

Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2023 Journal of Pakistan Society of Internal Medicine.
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