Original Research

Mean Platelet Volume as a Predictor of Severity of Acute IschaemicStroke Using Modified Rankin Score

Nasir Farooq Butt
Department of Medicine, King Edward Medical University, Lahore
Rabia Rathore
Department of Medicine, King Edward Medical University, Lahore
Hina Latif
Department of Medicine, King Edward Medical University, Lahore
Heba-Tul-Noor Heba-Tul-Noor
Department of Medicine, King Edward Medical University, Lahore
Hassan Mehmood
Department of Medicine, King Edward Medical University, Lahore
Fawad Ahmad Randhawa
Department of Medicine, King Edward Medical University, Lahore

✉ Correspondence: Hina Latif Email: hinalatif2011@gmail.com

DOI https://doi.org/10.70302/jpsim.v4i4.2357
Volume: 4, Issue 4 Pages: 284–288 Published: 29 Nov 2023
Received: 30 Jul 2023 Accepted: 17 Aug 2023 Published Online: 29 Nov 2023

Abstract

Objective

To determine the association of mean platelet volume in terms of predictor of severity of acute ischemic stroke using Modified Rankin Score (MRS).

Methods

From July 2019 to June 2021, this observational study was carried out at the Mayo Hospital Lahore's Departments of Medicine and Emergency. 225 patients in total were chosen utilizing the non-probability convenient sampling technique. Patients were divided into 2 groups according to their MRS scores (Group A: score 0 to 2, Group B: score 3 or higher). Blood samples were taken in order to test MPV. The MRS was used to determine the severity of an ischemic stroke.

Results

Out of 225 patients, 108 were assigned to Group A (MRS 0–2) and 117 to Group B (MRS 3 or higher). The mean±SD of MPV in Group B was 8.55 0.67, while it was 8.37 0.65 in Group A, which was statistically noteworthy (p=0.004). The effect of MPV on ischemic stroke was still statistically significant (OR: 1.579, p=0.3) after risk profiles linked to ischemic stroke were taken into account in the multivariate logistic regression model. The MPV had a significant discriminative value for predicting severe ischemic stroke based on MRS ≥ 3 from a mild stroke incidence (MRS < 3), as evidenced by the area under the ROC curve of 0.592 (95% CI: 0.43-0.6).

Conclusion

Mean Platelet volume can be a useful preliminary indicator which can be utilized in primary acute ischemic stroke patients as a marker of severity using Modified Rankin Score.

Keywords
Mean Platelet Volume acute ischemic stroke Modified Rankin Score

How to Cite This Article

Butt NF, Rathore R, Latif H, Heba-Tul-Noor H, Mehmood H, Randhawa FA. Mean Platelet Volume as a Predictor of Severity of Acute IschaemicStroke Using Modified Rankin Score. J Pak Soc Intern Med. 2023;4(4):284–288. doi:10.70302/jpsim.v4i4.2357

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2023 Journal of Pakistan Society of Internal Medicine.
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