Original Research

Frequency of Stroke in Patients Presenting with ChronicObstructive Pulmonary Disease

Sundus Rauf
North Medical Ward, King Edward Medical University, Mayo Hospital, Lahore, Pakistan
Sami Ullah Mumtaz
North Medical Ward, King Edward Medical University, Mayo Hospital, Lahore, Pakistan
Somia Iqtadar
North Medical Ward, King Edward Medical University, Mayo Hospital, Lahore, Pakistan
Zafar Niaz
North Medical Ward, King Edward Medical University, Mayo Hospital, Lahore, Pakistan
Mohsin Masud
North Medical Ward, King Edward Medical University, Mayo Hospital, Lahore, Pakistan
Israr Ul Haque
North Medical Ward, King Edward Medical University, Mayo Hospital, Lahore, Pakistan

✉ Correspondence: Sundus Rauf Email: sundusrauf77@gmail.com

DOI https://doi.org/10.70302/jpsim.v4i4.2359
Volume: 4, Issue 4 Pages: 293–296 Published: 29 Nov 2023
Received: 23 Jul 2023 Accepted: 11 Sep 2023 Published Online: 29 Nov 2023

Abstract

Objective

To determine the frequency of stroke in patients presenting with COPD.

Methods

This was a Cross sectional study conducted at North Medical Ward, Mayo Hospital, Lahore for Six months i.e. 28-7-2020 to 28-1-2021. Total 250 patients fulfilling the study criteria were enrolled. Then patients were evaluated by using spirometer and FEV1 and FVC were noted. Two groups were formed i.e. group I with COPD (FEV1/FVC<0.70) and group II without COPD. Then patients were asked for their medical record and history of stroke. If there was positive history of stoke, then it was noted. All this information was recorded on a predesigned proforma.

Results

The mean age of the patients was 60.21±19.32 years. There were 188 (75.2%) males and 62 (24.8%) females in this study. There were 72 (28.8%) patients with COPD and 178 (71.2%) without COPD. In this study there were 44 (17.6%) patients who were having stroke and 206 (82.4%) had no stroke. There was significant association between Stroke and COPD (p-value:<0.001)

Conclusion

It was concluded that frequency of stroke among COPD patients was 36.1%. Age, Gender, BMI, Hypertension, Diabetes and smoking had a significant impact on stroke frequency among COPD patients. Keeping in mind these results stroke screening should be carried out periodically by the pulmonologist to reduce it risk.

Keywords
Chronic Obstructive Pulmonary Disease Stroke FEV1 FVC

How to Cite This Article

Rauf S, Mumtaz SU, Iqtadar S, Niaz Z, Masud M, Haque IU. Frequency of Stroke in Patients Presenting with ChronicObstructive Pulmonary Disease. J Pak Soc Intern Med. 2023;4(4):293–296. doi:10.70302/jpsim.v4i4.2359

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

  1. Chen W, Thomas J, Sadatsafavi M, FitzGerald JM. Risk of cardiovascular comorbidity in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis. Lancet Respir Med. 2015;3(8):631-9.
  2. Terzikhan N, Verhamme KMC, Hofman A, Stricker BH, Brusselle GG, Lahousse L. Prevalence and incidence of copd in smokers and non-smokers: The rotterdam study. Eu J Epidemiol. 2016;31(8):785-92
  3. Morgan AD, Zakeri R, Quint JK. Defining the relationship between copd and cvd: What are the implications for clinical practice? Ther Adv Respir Dis. 2018;12:1753465817750524.
  4. Austin V, Crack PJ, Bozinovski S, Miller AA, Vlahos R. Copd and stroke: Are systemic inflammation and oxidative stress the missing links? Clin Sci. 2016;130(13):1039-50.
  5. Söderholm M, Inghammar M, Hedblad B, Egesten A, Engström G. Incidence of stroke and stroke subtypes in chronic obstructive pulmonary disease. European Journal of Epidemiology. 2016;31(2):159-68.
  6. Lin H-W, Chung C-L, Lin YS, Yu C-M, Lee C-N, Bien M-Y. Inhaled pharmacotherapy and stroke risk in patients with chronic obstructive pulmonary disease: A nationwide population based study using two-stage approach. PloS one. 2015;10(7):e0130102.
  7. Lahousse L, Vernooij MW, Darweesh SK, Akoudad S, Loth DW, Joos GF, et al. Chronic obstructive pulmonary disease and cerebral microbleeds. The rotterdam study. Am J Resp Crit care Med. 2013;188(7):783-8.
  8. Sinden NJ, Stockley RA. Systemic inflammation and comorbidity in copd: A result of ‘overspill’of inflammatory mediators from the lungs? Review of the evidence. Thorax. 2010;65(10):930-6.
  9. Man SP, Van Eeden S, Sin DD. Vascular risk in chronic obstructive pulmonary disease: Role of inflammation and other mediators. Canadian J Cardiol. 2012;28(6):653-61.
  10. Poels MM, Vernooij MW, Ikram MA, Hofman A, Krestin GP, van der Lugt A, et al. Prevalence and risk factors of cerebral microbleeds: An update of the rotterdam scan study. Stroke. 2010;41(10_suppl_1):S103-S6.
  11. Brusselle GG, Joos GF, Bracke KR. New insights into the immunology of chronic obstructive pulmonary disease. Lancet. 2011;378(9795):1015-26.
  12. Donaldson GC, Hurst JR, Smith CJ, Hubbard RB, Wedzicha JA. Increased risk of myocardial infarction and stroke following exacerbation of copd. Chest. 2010;137(5):1091-7.

Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2023 Journal of Pakistan Society of Internal Medicine.
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