Original Research

Frequency of Autonomic Neuropathy in Patients with RheumatoidArthritis

Rabia Rathore1
Department of Medicine, KEMU, Lahore
Saif ur Rab2
Shaukat Khanum Memorial Cancer Hospital,Lahore
Nasir Farooq Butt1
Department of Medicine, KEMU, Lahore
Hina Latif1
Department of Medicine, KEMU, Lahore
Heba Tul Noor1
Department of Medicine, KEMU, Lahore
Adil Iqbal1
Department of Medicine, KEMU, Lahore

✉ Correspondence: Rabia Rathore Email: rabiarathore25871@import.invalid

DOI https://doi.org/10.70302/jpsim.v5i1.2411
Volume: 5, Issue 1 (Women Issue) Pages: 407–412 Published: 28 Feb 2024
Received: 21 Oct 2023 Accepted: 14 Dec 2023 Published Online: 28 Feb 2024

Abstract

Objective

To assess the frequency of autonomic neuropathy (AN) in patients with rheumatoid arthritis.

Methods

This Cross sectional study was carried out at Department of Medicine, Mayo Hospital, Lahore, Pakistan, from March 2020 to February 2022. A total of 100 patients were registered in the study through Outpatient Department of Medicine, Mayo Hospital, Lahore. To assess cardiac autonomic neuropathy, the five cardiovascular reflex examinations listed by Ewing were performed that includes the effect of deep breathing, Valsalva maneuver as well as standing on the measurement of heart rate (HR),also blood pressure (BP) response to sustained handgrip and standing was noted. Grading of the cardiac AN was carried out in accordance with Agarwal D et al's description.

Results

The mean age of patients was 44.09 ± 10.06 years. There were 29 (29%) males and 71 (71%) females. The mean duration of disease was 7.88 ± 1.76 years with minimum duration of 5.5 years and maximum duration of 11 years. A total of 77 (77%) cases had autonomic neuropathy while rest of 23 (23%) cases did not have autonomic neuropathy. There were 23 (23%) cases who had mild, 32 (32%) had moderate and 16 (16%) cases had severe autonomic neuropathy.

Conclusion

It is concluded that more than in the 3rd quarter i.e. 77% cases of RA had Autonomic Neuropathy.

Keywords
: RheumatoidArthritis Autonomicdysfunction Chronic inflammatorydisorder Extra-articularmanifestations.

How to Cite This Article

Rathore R, Rab SU, Butt NF, Latif H, Noor HT, Iqbal A. Frequency of Autonomic Neuropathy in Patients with RheumatoidArthritis. J Pak Soc Intern Med. 2024;5(1):407–412. doi:10.70302/jpsim.v5i1.2411

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2024 Journal of Pakistan Society of Internal Medicine.
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