Amlodipine Poisoning with Transient Cardiomyopathy andConcurrent Benzodiazepine Overdose
Abstract
A 25 year old male with an intentional ingestion of amlodipine and benzodiazepine with suicidal intention, due to peer pressure and psychological distress, had experienced transient cardiomyopathy. This case depicts the improved left ventricular function after the successful management of poisoning with a timely conventional management strategy (i.e. via intravenous fluid, vasopressor and inotropic support and Glucagon and Insulin infusion with 10% Dextrose water, and calcium gluconate administration). Amlodipine is a longer acting dihydropyridine calcium channel blocker that effectively controls blood pressure for 24 hours. It is a commonly used and safe antihypertensive agent.1 Nevertheless, the overdose can have deleterious side effects.2-4 .Physician should have high index of suspicion of amlodipine poisoning in the patient having refractory shock with the history of drug overdose. As early recognition and timely management of acute amlodipine poisoning will result in successful outcome, like in our case.
How to Cite This Article
Akhlaq S, Aziz A, Mahmood SBZ. Amlodipine Poisoning with Transient Cardiomyopathy andConcurrent Benzodiazepine Overdose. J Pak Soc Intern Med. 2024;5(1):433–435. doi:10.70302/jpsim.v5i1.2416
Conflict of Interest
All authors declare no competing interests.
Funding
No specific funding was received for this research.
Funder information follows the Crossref Funder Registry standard.
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