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Frequency of Transaminitis in Patient with Dengue Fever in First Five Days of Illness: A Hospital Based Survey

Javeria Benyamin
Fatima Memorial Hospital Shadman, Lahore.
Sidra Anwar
Fatima Memorial Hospital Shadman, Lahore.
Kamran Rauf
Fatima Memorial Hospital Shadman, Lahore.

✉ Correspondence: Javeria Benyamin Email: javeriabenyamin222@gmail.com

DOI https://doi.org/10.70302/jpsim.v5i1.2419
Volume: 5, Issue 1 (Women Issue) Pages: 441–445 Published: 28 Feb 2024
Received: 14 Oct 2023 Accepted: 18 Dec 2023 Published Online: 28 Feb 2024

Abstract

Objective

To determine the frequency of transaminitis in patients with documented dengue fever in first five days of illness and their association with the disease severity.

Methods

A retrospective cross-sectional observational study including 382 patients with confirmed dengue serology admitted in Department of Medicine of Fatima Memorial Hospital Lahore during July 2022-July 2023. Patient demographics, presenting symptoms, clinical signs, laboratory parameters such as complete blood count (CBC) and liver function tests (LFTs) were collected and frequency of transaminitis was determined in patients correlating with disease severity in the first five days of illness. Comparisons were drawn between age groups and gender. P-value <0.05 and CI 95% were considered during analysis.

Results

Out of 382 patients, only 275 had reported transaminitis which is approximately 72% of total population. Significant association was found between transaminitis and severity of disease.

Conclusion

Overall frequency of transaminitis in otherwise healthy patients (not having liver disease history) was statistically significant and accounted for almost two thirds of the dengue patients whereas one third of the patients did not have transaminitis. Statistical relationship between transaminitis and severity of disease was also noted.

Keywords
Transaminitis Dengue fever.

How to Cite This Article

Benyamin J, Anwar S, Rauf K. Frequency of Transaminitis in Patient with Dengue Fever in First Five Days of Illness: A Hospital Based Survey. J Pak Soc Intern Med. 2024;5(1):441–445. doi:10.70302/jpsim.v5i1.2419

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2024 Journal of Pakistan Society of Internal Medicine.
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