Original Research

Transmissible Infection Profile and Hematological Parameters in Healthy Blood Donors and Trends in Unsuitability for Blood Donation

Khazina Ikram1
Riphah International University, Islamabad
Fawad Mahmood1
Riphah International University, Islamabad
Seher Obaid2
Northwest School of Medicine, Peshawar,
Ayesha Noor3
Quetta Institute of Medical Sciences, Quetta
Sadaf Nasir4
Islamabad Medical and Dental College, Islamabad,
Saira Nasr Malik5
Khyber Medical College/Khyber Teaching Hospital, Peshawar.

✉ Correspondence: Seher Obaid Email: sairamalik87@gmail.com

DOI https://doi.org/10.70302/jpsim.v5i3.2452
Volume: 5, Issue 3 Pages: 619–623 Published: 30 Aug 2024
Received: 11 Jul 2024 Accepted: 07 Aug 2024 Published Online: 30 Aug 2024

Abstract

Objective

This study assessed the prevalence of HIV, syphilis, dengue, malaria, HBV, HCV, and other transfusion-transmitted infections (TTIs) among healthy blood donors in Rawalpindi, Pakistan.

Methods

The investigation was carried out from January to September of 2022 at Al-Khidmat Raazi Diagnostic and Blood Bank. An Immunochromatographic Technique (ICT) was utilized to screen healthy blood donors for syphilis, malaria, dengue, HBsAg, anti-HCV, and anti-HIV antibodies. SPSS version 21, was used for statistical analysis.

Methods

This study examined blood donors who visited the Al-khidmat Raazi Diagnostic and Blood Bank between January and September of 2022. Blood donors underwent tests for dengue, malaria, syphilis, HIV, HBV, and HCV. To separate serum from blood, 5 ml of blood is collected in a sterile test tube and centrifuged at 3500 rpm for 5 minutes. Using ICT, screening was done for HbsAg, anti-HCV, anti-syphilis, and anti-HIV antibodies.

Results

Ninety percent of the blood donors had typical physical characteristics. Male donors made up all 298 (100%) of the healthy donors. Over the course of nine months, TTIs were tested for in 298 healthy blood donors. In our study, replacement donors made up 80% of the blood donors. The prevalence of malaria, dengue, HBV, HCV, HIV, syphilis, and other diseases was determined to be 12.5%, 13.4%, 12.8%, 6.7%, 0.7%, and 21.5% respectively. The hemoglobin level of 260 blood donors (87%) was 13mg/dl.

Conclusion

Donors frequently experience TTIs. Inadequate screening leads to transfusion-transmissible illnesses in healthy blood donors. Safe health practices and appropriate TTI screening could lower blood donors' risk of contracting communicable illnesses. To avoid unintentional transfusion reactions in both the recipient and the donor, the hospital must thoroughly screen donors for TTIs and unfitness.

Keywords
TTIs infection HBV Blood donor Syphilis Malaria HBV Dengue HIV

How to Cite This Article

Ikram K, Mahmood F, Obaid S, Noor A, Nasir S, Malik SN. Transmissible Infection Profile and Hematological Parameters in Healthy Blood Donors and Trends in Unsuitability for Blood Donation. J Pak Soc Intern Med. 2024;5(3):619–623. doi:10.70302/jpsim.v5i3.2452

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2024 Journal of Pakistan Society of Internal Medicine.
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