Original Research

Pediatric Acute Lymphoblastic Leukemia in Rawalpindi

Ikramullah Ikramullah1
Combined Military Hospital, Abbottabad,
Shafaq Saleem2
Gomal Medical College, Dera Ismail Khan
Ammar Bin Saad3
Ayub Medical College, Abbottabad
Naumana Rehman4
Khyber Medical College, Peshawar.
Maleeha Zia Mufti3
Ayub Medical College, Abbottabad
Saira Nasr Malik4
Khyber Medical College, Peshawar.

✉ Correspondence: Ikramullah Ikramullah Email: khanikramullah038@gmail.com

DOI https://doi.org/10.70302/jpsim.v5i3.2455
Volume: 5, Issue 3 Pages: 635–639 Published: 30 Aug 2024
Received: 16 Feb 2024 Accepted: 06 Aug 2024 Published Online: 30 Aug 2024

Abstract

Objective

To identify the incidences of ALL, it’s Diagnostic, clinical and its prognostic aspect from CMH Rawalpindi hospital Pakistan

Methods

Diagnosis and screening for ALL was done at CMH Rawalpindi from 2010-2021. During this time, 981 individuals under the age of 19 who had recently been diagnosed with acute lymphoblastic leukemia. Cytological, immunophenotypic, and cytogenetic criteria were employed to diagnose. Chi-square and Fisher's exact tests assessed prognostic factor associations.

Results

The collected data from 2010-2021, showed that Males predominated the incidence rate 626 (63.8%), average diagnostic age was 6.3-0.5 years. Results showed that 207(21.10%) were children less than 3 years old, 587(59.80%) were between 3-10 years old. While 187(19%) were above age of 10. After statistical analysis, patients at standard risk were found to be (496)50.5% while 485(49.5%) were at high risk. The collected data reported prevalence of ALL in (850)86.6% patients while 131(13.3%) patients were diagnosed with Albl. The survival rate of patients having disease and that of survival rate with disease free conditions was found in 655(66.7%) and 326(33.3%) patients respectively. Patients with normal nutritional status 726(74%), with moderate eating 165(16.80%) and eating severely 90(9.2%) was reported and analyzed.

Conclusion

ALL is found to be one of threat in young children and adolescence. There is a threat of relapse even after recovery from ALL when treated specifically in adolescence. Early prognosis and diagnosis of ALL is necessary to mitigate its effects and to avoid its recurrence. Health authorities in this regard should provide the required facilities to overcome this menace.

Keywords
Acute Lymphoblastic Leukemia Malignancy T-ALL Standard risk High risk.

How to Cite This Article

Ikramullah I, Saleem S, Saad AB, Rehman N, Mufti MZ, Malik SN. Pediatric Acute Lymphoblastic Leukemia in Rawalpindi. J Pak Soc Intern Med. 2024;5(3):635–639. doi:10.70302/jpsim.v5i3.2455

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2024 Journal of Pakistan Society of Internal Medicine.
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