To Determine the Frequency of Seizures in Patients Presented with Acute Stroke in Mayo Hospital, Lahore
Abstract
To determine the frequency of seizures in patients presenting with acute stroke in Mayo Hospital, Lahore.
This descriptive case series study was conducted in Medicine Department, Mayo Hospital, Lahore from June
10, 2020 to December 09, 2020. Total 215 cases with acute stroke were enrolled from the Medical Department of Mayo
Hospital, Lahore. Detailed history and physical examination were done by the researcher to ensure unbiased approach.
Study was done as per Helsinki declaration. The patients were followed for 14 days after stroke. The frequency of seizures
(according to operational definition) in patients with acute stroke within the first 14 days was noted. Data was scrutinized
in SPSS v25.0. Stratification for age, gender and type of stroke was done. Chi-square test was applied after stratification
and p-value ≤0.05 was taken as significant.
Total 215 patients presenting with acute stroke were enrolled in this study. There were 134(62.3%) males and
81(37.7%) females. Mean age of subjects was 55.9±15.4 years. Overall frequency of seizures in patients with acute stroke
was 40(18.6%).
Seizures are not uncommon after developing an acute stroke, hence very early referral of all such cases to
tertiary care hospitals must be encouraged. Quick management of acute stroke may subsequently decrease prevalence of
developing seizures resulting in a better outcome.
How to Cite This Article
Sulehria SB, Anjum S, Ather CAA, Haider MZ, Zahra S, Haider MZH. To Determine the Frequency of Seizures in Patients Presented with Acute Stroke in Mayo Hospital, Lahore. J Pak Soc Intern Med. 2024;5(4):703–706. doi:10.70302/jpsim.v5i4.2468
Conflict of Interest
All authors declare no competing interests.
Funding
No specific funding was received for this research.
Funder information follows the Crossref Funder Registry standard.
References
- World Health Organization. The WHO Stepwise approach to stroke surveillance. 2016.
- Norrving B, Kissela B. The global burden of stroke and need for a continuum of care. Neurology. 2015;80(3):5-12.
- Hart LA, Sibai BM. Seizures in pregnancy epilepsy, eclampsia, and stroke. Semin Perinatol. 2015;37(4):207-24.
- Wang G, Jia H, Chen C, Lang S, Liu X, Xia C, Sun Y, Zhang J. Analysis of risk factors for first seizure after stroke in Chinese patients. BioMed Res Int. 2013.
- Burneo JG, Fang J, Saposnik G. Investigators of the Registry of the Canadian Stroke N. Impact of seizures on morbidity and mortality after stroke: a Canadian multi-centre cohort study. Eur. J. Neurol. 2015;17(1):52–8. [6]
- Laccheo I, Ablah E, Heinrichs R, Sadler T, Baade L, Liow K. Assessment of quality of life among the elderly with epilepsy. Epilepsy Behav. 2017;12(2):257–61.
- Lees A. Retrospective study of seizure-related injuries in older people: a 10- year observation. Epilepsy Behav. 2015;19(3):441–4.
- Neil S.N. Graham, Siobhan Crichton, Michael Koutroumanidis, Charles D.A. Wolfe, Anthony G. Rudd. Incidence and Associations of Post stroke Epilepsy the Prospective South London Stroke Register. Stroke. 2013;44(3):605-11.
- Silverman IE, Restrepo L, Mathews GC. Post-stroke seizures. Arch Neurol. 2012;59(2):195–201.
- Pezzini A, Grassi M, Del-Zotto E, Giossi A, Volonghi I, Costa P, et al. Complications of acute stroke and the occurrence of early seizures. Cerebrovasc Dis. 2013;35(5):444-50.
- Camilo O, Goldstein LB. Seizures and Epilepsy after ischemic stroke. Stroke. 2014;35:1769–75.
- Mohamed C, Kissani N. Early seizures in acute stroke. Pan African Med J. 2015;20(1):1-5.
- Qazi TR, Siddiqui AI, Lakhair MA, Mahesar SA. Frequency of early seizures in patients of acute ischemic stroke. J Liaquat Uni Med Health Sci. 2016;15(03):143-6.
- Stefanidou M, Das RR, Beiser AS, Sundar B, Kelly-Hayes M, Kase CS, Devinsky O, Seshadri S, Friedman D. Incidence of seizures following initial ischemic stroke in a community-based cohort: The Framingham Heart Study. Seizure. 2017;47:105-10.
- Ropper AH, Brown RH, editors. Adam's and Victor's principles of neurology. 8th ed. Philadelphia: McGraw Hill; 2005.
- Sander JW. The epidemiology of epilepsy revisited. Curr Opin Neurol 2003;16:165-70.
- Benbir G, Ince B, Bozluolcay M. The epidemiology of post-stroke epilepsy according to stroke subtypes. Acta Neurol Scand 2006;114:8-12.
- Khealani BA, Ali S, Baig SM. Post-stroke seizures: descriptive study from a tertiary care centre in Pakistan. J Pak Med Assoc 2008;58:365-8.
- Dhanuka AK, Misra UK, Kalita J. Seizures after stroke: a prospective clinical study. Neurol India 2001;49:33-6.
- Cheung CM, Tsoi TH, Au-Yeung M, Tang AS. Epileptic seizure after stroke in Chinese patients. J Neurol 2003;250:839-43.
- Bladin CF, Alexandrov AV, Bellavance A, Bornstein N, Chambers B, Coté R, et al. Seizures after stroke: a prospective multicenter study. Arch Neurol 2000;57:1617-22.
- Arboix A, Comes E, Massons J, García L, Oliveres M. Relevance of early seizures for in-hospital mortality in acute cerebrovascular disease. Neurology 1996;47:1429-35.
- Lamy C, Domigo V, Semah F, Arquizan C, Trystram D, Coste J, et al. Early and late seizures after cryptogenic ischemic stroke in young adults. Neurology 2003;60:400-4.
- Mohr JP, Caplan LR, Melski JW, Goldstein RJ, Duncan GW, Kistler JP, et al. The Harvard Cooperative Stroke Registry: a prospective registry. Neurology 1978;28:754-62.
- Bladin CF, Alexandrov AV, Bellavance A, Bornstein N, Chambers B, Cote R, et al. Seizures after stroke: a prospective multicenter study. Arch Neurol 2000;57:1617-22.
- Kilpatrick CJ, Davis SM, Hopper JL, Rossiter SC. Early seizures after acute stroke. Risk of late seizures. Arch Neurol 1992;49:509-11.
- Giroud M, Gras P, Fayolle H, Andre N, Soichot P, Dumas R. Early seizures after acute stroke: a study of 1,640 cases. Epilepsia 1994;35:959-64.
- Silverman IE, Restrepo L, Mathews GC. Poststroke seizures. Arch Neurol 2002;59:195-201.
- Lamy C, Domigo V, Semah F, Arquizan C, Trystram D, Coste J, et al. Early and late seizures after cryptogenic ischemic stroke in young adults. Neurology 2003;60:400-4.
- Stroke epidemiological data of nine Asian countries. J Med Assoc Thai 2000;83:1-7.
- Burke TA, Venketasubramanian RN. The epidemiology of stroke in the East Asian region: a literature based review. Int J Stroke 2006;1:208-15.
- Lovett JK, Coull AJ, Rothwell PM. Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies. Neurology 2004;62:569-73.
- Hardie K, Hankey GJ, Jamrozik K, Broadhurst RJ, Anderson C. Ten-year risk of first recurrent stroke and disability after first-ever stroke in the Perth Community Stroke Study. Stroke 2004;35:731-5.
Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.