Original Research

The H. Pylori Infection, Erosive Esophagitis & Non-Erosive Reflux Disease in GERD

Muhammad Habib1
Mayo Hospital Lahore
Irfan Younus2
Aziz Bhatti Shaheed Teaching Hospital Gujrat
Malik Muhammad Waseem3
Services Hospital Lahore,
Adnan Qadir4
Islamic International Medical College Rawalpindi
Shama Iqbal5
Sheikh Zayed Medical College Rahim Yar Khan
Faisal Rasheed2
Aziz Bhatti Shaheed Teaching Hospital Gujrat

✉ Correspondence: Irfan Younus Email: irfanyounis7887@gmail.com

DOI https://doi.org/10.70302/jpsim.v5i4.2471
Volume: 5, Issue 4 Pages: 716–719 Published: 09 Dec 2024
Received: 26 Feb 2024 Accepted: 05 Nov 2024 Published Online: 09 Dec 2024

Abstract

Objective

To determine the prevalence of infection with Helicobacter pylori in GERD patients and compare the incidence of
erosive esophagitis and non-erosive reflux illness in those patients.

Methods

This descriptive cross sectional was done at Medical division of Mayo Hospital Lahore from 6th Dec 2021 to
6th June 2022.Total of 150 patients fulfilling the inclusion criteria were enrolled after taking informed consent. Endoscopy
was performed in all patients. Both non-erosive reflux disease and erosive esophagitis were found endoscopically. All
patients had tissue biopsies obtained for histopathology, which were then forwarded to the pathology lab for H. pylori
detection.

Results

Out of 150 patients, 58.7% (88) were female and 41.3% (62) were male. These patients were between the ages of
15 and 65. They were split into two groups: younger people, whose ages ranged from 15 to 40 (mean: 26.84 ± 7.478), and
middle-aged people, whose ages ranged from 41 to 65 (mean: 51.31 ± 7.378). 32% (48) of the population was in the
middle age bracket, while 68% (102) were among the young. 13.3% (20) of the patients had erosive esophagitis, while
86.7% (130) had non-erosive reflux illness. 20% (4) of patients with erosive esophagitis and 29.23% (38) of individuals
with non-erosive reflux disease had H pylori infection. (P < 0.3).

Conclusion

Patients with GERD are more likely to have non-erosive reflux disease than erosive esophagitis on endoscopy,
and non-erosive reflux disease is linked to a higher incidence of helicobacter infection.

Keywords
Gastroesophageal reflux disease (GERD) non-erosive reflux disease (NERD) and Helicobacter pylori (H.Pylori) Erosive esophagitis.

How to Cite This Article

Habib M, Younus I, Waseem MM, Qadir A, Iqbal S, Rasheed F. The H. Pylori Infection, Erosive Esophagitis & Non-Erosive Reflux Disease in GERD. J Pak Soc Intern Med. 2024;5(4):716–719. doi:10.70302/jpsim.v5i4.2471

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2024 Journal of Pakistan Society of Internal Medicine.
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