Original Research

Diagnostic Accuracy of CT PNS in Diagnosing Fungal Sinusitis and its Relation with Endoscopy and Histopathological Findings

Hina Hafeez Abbasi1
Rawalpindi Medical University, Rawalpindi
Fizza Batool2
Rawalpindi Teaching Hospital, Rawalpindi
Madiha Azam3
Benazir Bhutto Hospital, Rawalpindi
Hussnain Qadir4
Govt. Rural Dispensary, District Khanewal
Mahwish Shoaib5
Punjab Institute of Neurosciences, Lahore
Zeeshan Tariq6
Lahore General Hospital, Lahore

✉ Correspondence: Hina Hafeez Abbasi Email: hinahafeezabbasi40521@import.invalid

DOI https://doi.org/10.70302/jpsim.v5i4.2477
Volume: 5, Issue 4 Pages: 745–749 Published: 09 Dec 2024
Received: 16 Feb 2024 Accepted: 03 Nov 2024 Published Online: 09 Dec 2024

Abstract

Objective

To assess the diagnostic accuracy of CT PNS in diagnosing fungal sinusitis and its relation with endoscopy and
histopathology

Methods

This cross sectional retrospective study was conducted at Benazir Bhutto Hospital, Rawalpindi from July 2022
to July 2023. Data of 153 individuals was collected who underwent CT PNS, Endoscopy and histopathology. Data was
analyzed in SPSS version. 26.

Results

The mean age of individuals was 39.38 ± 7.05 years. Out of 153 individuals, 87 (56.9%) were males and 66
(43.1%) were females. On CT PNS, out of 153 individuals, 122 (79.7%) individuals were positive for fungal sinusitis but 31
(20.3%) were found negative. On histopathology, results were almost same as results obtained on CT, on histopathology
i.e. 119 (77.8%) positive and 34 (22.2%) negative. Against endoscopy as well as against histopathology, CT PNS showed
sensitivity and specificity of 95% and 73.5%, respectively. The overall diagnostic accuracy of CT PNS was 90.2% against
endoscopy.

Conclusion

Thus CT PNS serves as a good diagnostic tool for detection of fungal sinusitis and a reliable guide for the
surgeon, since diseases confined to the nose and paranasal sinuses may be effectively done under endoscopic techniques.

Keywords
computed tomography fungal sinusitis endoscopy histopathology paranasal sinus.

How to Cite This Article

Abbasi HH, Batool F, Azam M, Qadir H, Shoaib M, Tariq Z. Diagnostic Accuracy of CT PNS in Diagnosing Fungal Sinusitis and its Relation with Endoscopy and Histopathological Findings. J Pak Soc Intern Med. 2024;5(4):745–749. doi:10.70302/jpsim.v5i4.2477

⭳ Download PDF

Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

  1. Gorovoy IR, Kazanjian M, Kersten RC, Kim HJ, Vagefi MR. Fungal rhinosinusitis and imaging modalities. Saudi Journal of Ophthalmology. 2012;26(4):419-26.
  2. Dhanani R, Ghaloo SK, Salam B, Pasha HA, Yousuf FH, Ikram M. Prevalence of allergic fungal sinusitis among patients with nasal polyposis. JPMA The Journal of the Pakistan Medical Association. 2021;71(6):1605-7.
  3. Bulut HT, Kaplan E, ÇORAPLI M. Acute and chronic invasive fungal sinusitis and imaging features: A review. Journal of Surgery and Medicine. 2021;5(12):1214-7.
  4. Aribandi M, McCoy VA, Bazan III C. Imaging features of invasive and noninvasive fungal sinusitis: a review. Radiographics. 2007;27(5):1283-96.
  5. Chakrabarti A, Denning DW, Ferguson BJ, Ponikau J, Buzina W, Kita H, et al. Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies. The Laryngoscope. 2009;119(9):1809-18.
  6. Reddy CEE, Gupta AK, Singh P, Mann SB. Imaging of granulomatous and chronic invasive fungal sinusitis: comparison with allergic fungal sinusitis. Otolaryngology—Head and Neck Surgery. 2010;143(2):294-300.
  7. Mathur S, Karimi A, Mafee M. Acute optic nerve infarction demonstrated by diffusion-weighted imaging in a case of rhinocerebral mucormycosis. American journal of neuroradiology. 2007;28(3):489-90.
  8. Aziz M, Mailk S, Manzoor M, Aziz S, Aziz M, Manzoor M. Diagnosis of Fungal Sinusitis; is Fungal Culture a Must? Pakistan Armed Forces Medical Journal. 2023;73(2):418-21.
  9. Manchanda S, Semalti K, Bhalla AS, Thakar A, Sikka K, Verma H. Revisiting rhino-orbito-cerebral acute invasive fungal sinusitis in the era of COVID-19: pictorial review. Emergency radiology. 2021;28(6):1063-72.
  10. Meng Y, Zhang L, Piao Y, Lou H, Wang K, Wang C. The use of magnetic resonance imaging in differential diagnosis of allergic fungal sinusitis and eosinophilic mucin rhinosinusitis. Journal of thoracic disease. 2019;11(8):3569.
  11. Deutsch PG, Whittaker J, Prasad S. Invasive and non-invasive fungal rhinosinusitis—a review and update of the evidence. Medicina. 2019;55(7):319.
  12. Suresh S, Arumugam D, Zacharias G, Palaninathan S, Vishwanathan R, Venkatraman V. Prevalence and clinical profile of fungal rhinosinusitis. Allergy & Rhinology. 2016;7(2):ar. 2016.7. 0156.
  13. Iqbal J, Rashid S, Darira J, Shazlee MK, Ahmed MS, Fatima S. Diagnostic accuracy of CT scan in diagnosing paranasal fungal infection. J Coll Physicians Surg Pak. 2017;27(5):271-4.
  14. Kandukuri R, Phatak S. Evaluation of sinonasal diseases by computed tomography. Journal of clinical and diagnostic research: JCDR. 2016;10(11):TC09.
  15. Nathan K, Majhi SK, Bhardwaj R, Gupta A, Ponnusamy S, Basu C, et al. The Role of Diagnostic Nasal Endoscopy and a Computed Tomography Scan (Nose and PNS) in the Assessment of Chronic Rhinosinusitis: A Comparative Evaluation of the Two Techniques. Sinusitis. 2021;5(1):59-66.
  16. Nicolai P, Lombardi D, Tomenzoli D, Villaret AB, Piccioni M, Mensi M, et al. Fungus ball of the paranasal sinuses: experience in 160 patients treated with endoscopic surgery. The Laryngoscope. 2009;119(11):2275-9.
  17. Khattar VS, Hathiram B. Radiologic appearances in fungal rhinosinusitis. Otorhinolaryngology Clinics. 2009;1:15-23.
  18. Khullar T, Kumar J, Sindhu D, Garg A, Meher R. CT Imaging Features in Acute Invasive Fungal Rhinosinusitis- Recalling the Oblivion in the COVID Era. Current problems in diagnostic radiology. 2022;51(5):798-805.

Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2024 Journal of Pakistan Society of Internal Medicine.
📃 In This Issue View All
Original Article Outcomes of Laparoscopic Cholecystectomy in Acute Cholecystitis: A Retrospective Analysis Raza SH, Butt N, Qureshi AM Original Article Impact of Diabetes Mellitus on Post-Operative Wound Healing in General Surgery Siddiqui FA, Noor M, Akhtar W Review Article Thyroid Disorders in Pregnancy: Clinical Implications and Management Strategies Baig BI, Usman A Original Article Prevalence of Hypertension Among Urban Adults in Pakistan: A Cross-Sectional Study Khan TM, Ahmed S, Malik RA Original Article Cervical Cancer Screening Awareness Among Rural Women in Punjab Bibi S, Anjum R, Hassan F
👥 More by These Authors
Review Article Statin Therapy in Non-Alcoholic Fatty Liver Disease: A Systematic Review Nawaz F, Cheema HA, Mehmood Y Review Article Antibiotic Resistance Patterns in Community-Acquired Pneumonia: Emerging Trends Hussain I, Farooq Z Original Article Serum Ferritin as a Prognostic Marker in COVID-19 Severity: A Hospital-Based Study Rehman N, Sheikh I, Javed K Original Article Neonatal Sepsis: Bacteriological Profile and Antibiogram in a Tertiary Care Hospital Iqbal M, Rashid T
🔗 Related Articles By Keywords
Review Article Thyroid Disorders in Pregnancy: Clinical Implications and Management Strategies Baig BI, Usman A Original Article Prevalence of Hypertension Among Urban Adults in Pakistan: A Cross-Sectional Study Khan TM, Ahmed S, Malik RA Original Article Cervical Cancer Screening Awareness Among Rural Women in Punjab Bibi S, Anjum R, Hassan F Original Article Comparison of Ultrasound-Guided versus Landmark-Based Central Venous Catheter Insertion Zafar S, Gillani SA