Original Research

Effect of Increased Portal Vein Diameter on Portal Vein Thrombosis in Decompensated Chronic Liver Disease

Raffad Raffad1
1Services Institute of Medical Science
Kafayat-Ullah Malik1
1Services Institute of Medical Science
Asma Kamal1
1Services Institute of Medical Science
Asifa Kamal1
1Services Institute of Medical Science
Qurat-ul Ain2
Lahore General Hospital
Iram Iqbal1
1Services Institute of Medical Science

✉ Correspondence: Raffad Raffad Email: raffadraffad41371@import.invalid

DOI https://doi.org/10.70302/jpsim.v6i1.2507
Volume: 6, Issue 1 Pages: 32–37 Published: 10 Mar 2025
Received: 19 Oct 2024 Revised: 16 Jan 2025 Accepted: 22 Feb 2025 Published Online: 10 Mar 2025

Abstract

Objective

To determine the association between portal vein diameter and portal vein thrombosis in patients with decompensated chronic liver disease.

Methods

This case-control study was conducted at the Department of Medicine, Lahore General Hospital, Lahore, involving 84 patients with decompensated chronic liver disease observed over six months. Of these, 42 patients who developed portal vein thrombosis were categorized as cases, while the remaining 42 served as controls. Portal vein diameter was measured using ultrasonography, and chi-square analysis was used to test the association between portal vein diameter and portal vein thrombosis. Statistical analysis was performed using SPSS version 17.0.

Results

Among the 84 patients, 32 (38%) were female, and 52 (62%) were male. The average age was 54.4 ± 2.2 years. Portal vein diameter greater than 13 mm was observed in 20 (24%) patients. No significant association was found between portal vein diameter and portal vein thrombosis (p-value = 0.306).

Conclusion

Portal vein diameter is not associated with portal vein thrombosis in patients with decompensated chronic liver disease. Larger, multicenter studies are needed to validate these findings and identify preventive measures.

Keywords
Portal Vein Thrombosis Liver Cirrhosis Portal Vein Diameter Child Pugh's

How to Cite This Article

Raffad R, Malik K, Kamal A, Kamal A, Ain Q, Iqbal I. Effect of Increased Portal Vein Diameter on Portal Vein Thrombosis in Decompensated Chronic Liver Disease. J Pak Soc Intern Med. 2025;6(1):32–37. doi:10.70302/jpsim.v6i1.2507

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2025 Journal of Pakistan Society of Internal Medicine.
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