Socio-Demographic and Behavioral Factors in Patients with DelayedDiagnosis of Human Immunodeficiency Virus: A Cross-SectionalStudy
Abstract
To find socio-demographic characteristics and behavioral factors of patients presenting in the late stage of HIV infection
This descriptive retrospective, cross sectional study was conducted at District Headquarter (DHQ) Teaching Hospital, Kohat Development Authority (KDA), Kohat from April 2020 to September 2020. Socio-demographic data was collected from patients record registered at HIV care center Kohat from either gender having age greater than 15 years with CD4 count at the time of diagnosis less than 350/mm3, or patient presenting with an AIDS defining illness on a pre-designed form. Descriptive statistics were applied to find characteristics of patients with late HIV diagnosis.
A total of 152 patients had a CD4 count less than 350/mm3 at the time of diagnosis and registration at the HIV care center DHQ Teaching hospital. There were 87 (57.2%) males and 53 (34.9%) females. Majority of patients belonged to the age group of 31-45 years (40.8%), were unemployed (59.2%), married (63.2%) and were from area of Bannu (19.1%). A significant number of patients had a history of travelling abroad and were using smokeless tobacco while majority of patients didn’t know about HIV infection and never visited health care worker in last year before registration at HIV Care Center Kohat.
Delayed diagnosis of HIV is common in male, unemployed patients, with a history of travelling abroad and married patients with majority of patients having no knowledge about HIV infection. Public health authorities shall implement new methods of expanding the realm of diagnostic testing as well as targeting those populations at a higher risk i.e., unemployed, substance abuse history, uneducated and having history of travel abroad, will help in early HIV diagnosis, avoiding AIDS defining conditions and mortality associated with HIV virus infection.
How to Cite This Article
Naim F, Naeem A, Shah F, Islam U, Adnan S, Hamid M. Socio-Demographic and Behavioral Factors in Patients with DelayedDiagnosis of Human Immunodeficiency Virus: A Cross-SectionalStudy. J Pak Soc Intern Med. 2025;6(2):146–152. doi:10.70302/jpsim.v6i2.2528
Conflict of Interest
All authors declare no competing interests.
Funding
No specific funding was received for this research.
Funder information follows the Crossref Funder Registry standard.
References
- Levi J, Raymond A, Pozniak A, Vernazza P, Kohler P, Hill A. Can the UNAIDS 90-90-90 target be achieved A systematic analysis of national HIV treatment cascades. BMJ Global Health. 2016;1(2):e000010.
- Sidibé M, Loures L, Samb B. The UNAIDS 90–90–90 target: a clear choice for ending AIDS and for sustainable health and development. J Int AIDS Soc. 2016;19(1):21133.
- Koirala S, Deuba K, Nampaisan O, Marrone G, Ekström AM, group C-S. Facilitators and barriers for retention in HIV care between testing and treatment in Asia—a study in Bangladesh, Indonesia, Lao, Nepal, Pakistan, Philippines and Vietnam. PLoS One. 2017;12(5):e0176914.
- Mojumdar K, Vajpayee M, Chauhan NK, Mendiratta S. Late presenters to HIV care and treatment, identification of associated risk factors in HIV-1 infected Indian population. BMC Public Health. 2010;10(1):416.
- Cheng W, Tang W, Han Z, Tangthanasup TM, Zhong F, Qin F, et al. Late presentation of HIV infection: prevalence, trends, and the role of HIV testing strategies in Guangzhou, China, 2008–2013. BioMed Res Int. 2016; http://dx.doi.org/10.1155/2016/1631878. doi:10.1155/2016/1631878
- Xie J, Hsieh E, Sun M-q, Wang H-l, Lv W, Fan H-w, et al. Delays in HIV diagnosis and associated factors among patients presenting with advanced disease at a tertiary care hospital in Beijing, China. PloS One. 2017;12(8): e0182335.
- Harris J, Khatri R. Late diagnosis of HIV in the United Kingdom: An evidence review. 2015.
- Puglia M, Stasi C, Da Frè M, Voller F. Prevalence and characteristics of HIV/HBV and HIV/HCV coinfections in Tuscany. Braz J Infect Dis. 2016;20:330-4.
- Dailey AF, Hoots BE, Hall HI, Song R, Hayes D, Fulton Jr P, et al. Vital signs: human immunodeficiency virus testing and diagnosis delays—United States. Morbid Mort Weekly Rep. 2017;66(47):1300.
- Brännström J, Svedhem Johansson V, Marrone G, Wendahl S, Yilmaz A, Blaxhult A, et al. Deficiencies in the health care system contribute to a high rate of late HIV diagnosis in Sweden. HIV Med. 2016;17(6):425-35.
- Arbona SI, Barro AS. Peer Reviewed: Exploring the Spatial Determinants of Late HIV Diagnosis in Texas. Prevent Chron Dis. 2020;17(1):E96.
- Yasin F, Rizk C, Taylor B, Barakat LA. Substantial gap in primary care: older adults with HIV presenting late to care. BMC Geriatrics. 2020;20(1):1-5.
- Oluwalana MO, Awolude OA, Gao Z, Daley PK. The epidemiology of delayed HIV diagnosis in Ibadan, Nigeria. Int J STD AIDS. 2022;33(9):829-36.
- Chone JS, Abecasis AB, Varandas L. Determinants of Late HIV Presentation at Ndlavela Health Center in Mozambique. Int J Environ Res Public Health. 2022;19(8):4568.
- Gesesew HA, Ward P, Woldemichael K, Mwanri L. Late presentation for HIV care in Southwest Ethiopia in 2003–2015: prevalence, trend, outcomes and risk factors. BMC Infect Dis. 2018;18(1):59.
- Prevalence of Late Presenters and Advanced HIV Disease in HIV Patients and Their Related Factors in Iran: Results from 19 Years of National Surveillance HIV Data. AIDS Res Human Retroviruses. 2022;38(12):890-7.
- Robertson M, Wei SC, Beer L, Adedinsewo D, Stockwell S, Dombrowski JC, et al. Delayed entry into HIV medical care in a nationally representative sample of HIV-infected adults receiving medical care in the USA. AIDS Care. 2016;28(3):325-33.
- Ali H, Zakar R, Junaid K, Khan A, Fischer F. Frequency and reasons for delayed treatment initiation after HIV diagnosis: cross-sectional study in Lahore, Pakistan. BMC Public Health. 2021;21(1):1000.
- Fuge TG, Tsourtos G, Miller ER. Risk factors for late linkage to care and delayed antiretroviral therapy initiation among adults with HIV in sub-Saharan Africa: a systematic review and meta-analyses. Int J Infect Dis. 2022;122:885-904.
- Madiba S, Ralebona E, Lowane M, editors. Perceived stigma as a contextual barrier to early uptake of HIV testing, treatment initiation, and disclosure; the case of patients admitted with AIDS-related illness in a rural hospital in South Africa. InHealthcare. 2021;9(8):962.
- Fatukasi TV, Cole SR, Moore RD, Mathews WC, Edwards JK, Eron JJ, et al. Risk factors for delayed antiretroviral therapy initiation among HIV-seropositive patients. PLoS One. 2017;12(7):e0180843.
- Mwamba C, Beres LK, Topp SM, Mukamba N, Simbeza S, Sikombe K, et al. I need time to start antiretroviral therapy’: understanding reasons for delayed ART initiation among people diagnosed with HIV in Lusaka, Zambia. Ann Med. 2022;54(1):830-6.
- Frentz D, Wensing AM, Albert J, Paraskevis D, Abecasis AB, Hamouda O, et al. Limited cross-border infections in patients newly diagnosed with HIV in Europe. Retrovirol. 2013;10:1-10.
- Trepka MJ, Fennie KP, Sheehan DM, Lutfi K, Maddox L, Lieb S. Late HIV diagnosis: differences by rural/urban residence, Florida, 2007–2011. AIDS Patient Care STDs. 2014;28(4):188-97.
- Bedert M, Davidovich U, de Bree G, van Bilsen W, van Sighem A, Zuilhof W, et al. Understanding reasons for HIV late diagnosis: a qualitative study among HIV-positive individuals in Amsterdam, The Netherlands. AIDS and Behavior. 2021;25:2898-906.
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