Original Research

Prevalence of Adverse Donor Reactions among Healthy Blood DonorsPresenting in a Tertiary Care Hospital Blood Bank

Irfan Ranjha1
Allama Iqbal Medical College, Lahore, Pakistan
Hammad Tufail Chaudhary2
Taif University, Taif, Saudi Arabia
Irfan Amin1
Allama Iqbal Medical College, Lahore, Pakistan
Tooba Fateen1
Allama Iqbal Medical College, Lahore, Pakistan
Muhammad Saeed3
Kohsar University, Murree, Pakistan

✉ Correspondence: Irfan Ranjha Email: irfanranjha43291@import.invalid

DOI https://doi.org/10.70302/jpsim.v6i3.2544
Volume: 6, Issue 3 Pages: 239–244 Published: 23 Aug 2025
Received: 14 Feb 2025 Revised: 25 Feb 2025 Accepted: 28 Jul 2025 Published Online: 23 Aug 2025

Abstract

Objectives

To determine the incidence and types of adverse donor reactions among healthy blood donors during the blood donation process.

Methods

In this descriptive cross-sectional study, which was carried out at Blood Bank Jinnah Hospital, Lahore, over a period of six months from Aug 2023 to Jan 2024, a total of 550 healthy blood donors aged 18-60 years fulfilling the donation criteria were enrolled. After the informed consent, the study participants were observed during the whole donation process. Collected data were analyzed using SPSS software.

Results

Data from 550 donors consisting of 543 males and 7 females revealed mean age, height and weight of 28 years, 167 cm and 71 kg respectively. 484 (88%) were Rh positive blood groups and 66 (12%) were Rh negative groups. 28 (5.1%) donors experienced some adverse reactions and all were males. 8 (28%) of 28 were donating for the first time. All the reactions were mild to moderate in nature and no medical emergency or life- threatening situation appeared. 8 (28%) had slow pulse and fall in BP, 5 (18%) had nausea, 3 (10%) fainted, 3 (10%) were double pricked, 2 (7%) experienced warmth and head sweating, 2 (7%) had cold extremities, 2 (7%) had pain at the local site, 1 (4%) vomited, 1 (4%) felt fatigue, and 1 (4%) developed a hematoma.

Conclusion

Blood donation is a safe and risk-free procedure as only a few donors have experienced mild to moderate reactions. Proper training of blood bank staff and counselling of blood donors can reduce these adverse events more effectively.

Keywords
Blood Donation Blood Donor Adverse reactions Blood bank Tertiary care hospital Lahore.

How to Cite This Article

Ranjha I, Chaudhary HT, Amin I, Fateen T, Saeed M. Prevalence of Adverse Donor Reactions among Healthy Blood DonorsPresenting in a Tertiary Care Hospital Blood Bank. J Pak Soc Intern Med. 2025;6(3):239–244. doi:10.70302/jpsim.v6i3.2544

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Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2025 Journal of Pakistan Society of Internal Medicine.
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