Original Research

Comparison of Efficacy of Open Testicular Biopsy and SpermExtraction (TESE) versus Testicular Sperm Aspiration (TESA) interms of Sperm Retrieval Rate (SRR) in patients of Non-ObstructiveAzoospermia (NOA)

Adnan Rehman
Mayo Hospital, Lahore Pakistan
Fawad Nasrullah
Mayo Hospital, Lahore Pakistan
Ahmad Kamal
Mayo Hospital, Lahore Pakistan
Bilal Arshad
Mayo Hospital, Lahore Pakistan
Junaid Anwar
Mayo Hospital, Lahore Pakistan
Shahzaman Shahzaman
Mayo Hospital, Lahore Pakistan

✉ Correspondence: Adnan Rehman Email: adnanrehman419@gmail.com

DOI https://doi.org/10.70302/jpsim.v7i2.2620
Volume: 7, Issue 2 Pages: 101–103 Published: 03 Jun 2026
Received: 16 Jul 2025 Revised: 22 Apr 2026 Accepted: 03 May 2026 Published Online: 03 Jun 2026

Abstract

Objective

Objective of our study was to compare the yield of TESE versus TESA in terms of SRR in patients of NOA.

Methods

This randomized clinical trial was conducted in Department of Urology, Mayo Hospital Lahore. Patients diagnosed with NOA were selected and written informed consent was obtained. Baseline demographic and clinical information was recorded. Patients were then randomly allocated to two groups. Group A patients underwent TESE while TESA was performed in Group B patients. SRR of both groups were assessed and compared.

Results

Mean age of patients undergoing TESE and TESA was 29.73 ± 4.57 and 27.73 ± 4.88 years respectively (p = 0.766). Mean BMI of patients in undergoing TESE was 21.93 ± 1.24 kg/m2 while mean BMI of patients undergoing TESA was 22.46 ± 1.49 kg/m2 (p = 0.783). SRR of TESE was 66.6% while SRR of TESA was 40.0% (p = 0.038).

Conclusion

TESE was found to be more effective sperm retrieval technique in patients of NOA.

Keywords
Non-obstructive Azoospermia TESA TESE.

How to Cite This Article

Rehman A, Nasrullah F, Kamal A, Arshad B, Anwar J, Shahzaman S. Comparison of Efficacy of Open Testicular Biopsy and SpermExtraction (TESE) versus Testicular Sperm Aspiration (TESA) interms of Sperm Retrieval Rate (SRR) in patients of Non-ObstructiveAzoospermia (NOA). J Pak Soc Intern Med. 2026;7(2):101–103. doi:10.70302/jpsim.v7i2.2620

Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

References

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2026 Journal of Pakistan Society of Internal Medicine.
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