Adult Type BCR-ABL Positive CML: A Case Report of SouthernPunjab

Authors

Abstract

Chronic Myeloid Leukemia is the commonest type of myeloproliferative neoplasm. Peak age group of this illness is 27 to 66 years. The purpose of this case report is to emphasize the occurrence of rare cases and to help clinicians in diagnosing diseases with uncommon presentation. Current case report study was performed in Sheikh Zayed Medical College / Hospital Rahim Yar Khan, Pakistan from february 2022 to March 2022. A 17 years old male patient was included in this study. Complete Blood Count with peripheral smear, bone marrow aspiration and trephine biopsy were performed in Hematology department Sheikh Zayed Hospital Rahim Yar Khan, while fluorescence in situ hybridization analysis for Bcr-Abl fusion gene was performed at Agha Khan University Hospital Laboratory Karachi. Translocation was detected (98%) amongst 200 nuclei scored. Based on this study, possibility of chronic myeloid leukemia in young patients must not be ignored.

Keywords:

Chronic myeloid leukemia, Flourescence in situ hybridization, Bcr-Abl.

Published

2025/03/10