Prevalence and Impact of COVID-19 in Immuno-compromised Individuals: An Experience from a Private Outpatient Setting of South Punjab, Pakistan
AbstractTo find out the prevalence and impact of COVID-19 on immunocompromised patients visiting outpatient department of a private healthcare facility of South Punjab, Pakistan.
MethodsThis cross-sectional study was done at Outpatient Department of Aleena Hospital, Bahawalpur, Pakistan from 1st June 2020 to 30th December 2020. We included a total of 197 patients of both genders aged between 15 to 90 years visiting outpatient department of Aleena Hospital for various medical reasons. All patients underwent antibody testing for COVID-19 adopting immunochromatography for both IgG and IgM. A patient was labeled as immunocompromised if having diabetes mellitus or liver cirrhosis.
Results In a total of 197 patients, 122 (61.9%) were male. Overall, mean age was 45.1±13.3 years ranging 15 to 90 years. A total of 50 (25.4%) cases were antibody positive for COVID-19. BMI ≥ 25 (p=0.045), and “been to close proximity with someone who travelled outside/inside the country” (p=0.014) were noted to have significant association with COVID-19 positive cases while all other variables had insignificant association (p>0.05). Presence of diabetes mellitus was noted to have significant association with COVID-19 antibody positivity (p=0.002). Overall, no significant association of immunocompromised status and COVID-19 antibodies positivity was observed (p=0.090).
Conclusion Prevalence of positive COVID-19 antibodies was very high among patients visiting outpatient department of a private healthcare setting of South Punjab, Pakistan. Immunocompromised individuals were not found to have any significant association with COVID-19 infections.
Keywords:COVID-19, diabetes mellitus, immunocompromised, polymerase chain reaction.
This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments firstname.lastname@example.org