Outcomes in Critical COVID 19 Infection Affected by Pre-Existing Diabetes Mellitus
AbstractObjective: To determine the effect of pre-existing diabetes mellitus on disease course in COVID-19 infection. Methods: This retrospective observational study was done from Jan 2021 to August 2021. We included patients with COVID-19 infection having a positive PCR for SARS-CoV-2. Exclusion criteria included missing data or a negative PCR for SARS-CoV-2. Patients were selected using consecutive sampling. Length of stay and death within hospital were compared amongst diabetic and non- diabetic patients. Results: The 279 patients were aged 52.53± 11.31 years. Of these, 216 (77.42%) were males and 92 (32.97%) had diabetes. They remained admitted for 10.18± 3.13 days. The period of hospitalization was similar in diabetics and non- diabetics (10.70± 3.51 days vs 9.92± 2.91 days; p=0.052). Amongst the diabetics, 43(46.74%) died in hospital in comparison with 53 (39.55%) non- diabetics (p=0.002). The risk of in-hospital death in diabetics was 1.673 (95% CI 1.207 - 2.319). Conclusion: Diabetes mellitus is linked with greater risk of death, longer duration of hospital stay and higher need for critical care and novel therapy in COVID-19 infection.
Keywords:hospital stay, mortality, pandemic, pneumonia
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