A Study on a 21years Female Patient with Resected Pituitary Macroadenoma Presented with Persistently Raised Growth Hormone Levels and Resistant Diabetes Mellitus


  • Author- Faizan Banaras, Ramish Fayyaz, Mahnoor Ashfaq, Khola Fayaz, Tehrim Tahir, Ali Raza


Pituitary neuroendocrine tumors affect round about 5% of the general population. Pituitary macroadenomas have a size greater than 10mm, while microadenoma has a size less than 10mm.4 Acromegaly is a rare but fatal disorder mainly due to excessive growth hormone (GH) production from pituitary adenoma and a secondary rise in IGF-1 levels. It is characterized by physical disfigurement mainly face and limbs. The prevalence of acromegaly is 40 to 70 cases per million inhabitants with an annual incidence rate of 3 to 4 per million.5 The treatment options consist of pituitary surgery with the best approach of endonasal transsphenoidal hypophysectomy. The drugs used for prolactinoma and somatotrophic adenoma are dopamine agonists and somatostatin analogues respectively.